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Allergy, Asthma & Clinical Immunology
Published in: Allergy, Asthma & Clinical Immunology 2/2014

Open Access 01-12-2014 | Meeting abstract

Transcriptional networks in whole blood of asthmatics

Authors: Young Woong Kim, Amrit Singh, Casey P Shannon, Gail M Gauvreau, Scott J Tebbutt

Published in: Allergy, Asthma & Clinical Immunology | Special Issue 2/2014

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Excerpt

Allergen inhalation challenge causes significant changes in the blood transcriptomes of mild atopic asthmatic individuals [1]. Systems biology approaches have been used to identify transcriptional networks that reflect underlying disease processes. Such networks provide insights into the correlation patterns among genes and may identify specific molecular processes associated with asthmatic responses. Transcriptional networks can be identified using blood expression data and are associated with allergen-induced asthmatic responses. …
Literature
1.
Kam SH, Singh A, He JQ, Ruan J, Gauvreau GM: Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals. J Asthma. 2012, 49: 219-226. 10.3109/02770903.2011.654300.CrossRefPubMed
2.
Metadata
Title
Transcriptional networks in whole blood of asthmatics
Authors
Young Woong Kim
Amrit Singh
Casey P Shannon
Gail M Gauvreau
Scott J Tebbutt
Publication date
01-12-2014
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1710-1492-10-S2-A58

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