Published in:
Open Access
01-06-2014 | Meeting abstract
Screening for lung cancer with Low-Dose Computed Tomography: a systematic review of the evidence
Authors:
Sotiria-Maria E Iliopoulou, Antonis A Kousoulis
Published in:
Tobacco Induced Diseases
|
Special Issue 1/2014
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Excerpt
Tobacco use is the principal risk factor for lung cancer. Lung cancer is the most common cause of cancer death worldwide. When identified clinically, most patients have advanced disease with poor prognosis: the mortality rate at stage IV is over 95.0%, whereas the 5-year survival rate is over 73.0% at stage I. Thus, there is a growing interest in the early detection of lung cancer with Low-Dose Computed Tomography (LDCT) scans. The objective of the study is to conduct a systematic review of the evidence in Randomized Clinical Trials (RCTs) assessing the effect of screening with LDCT on lung cancer mortality and assess benefit and harm. …