Published in:
Open Access
01-06-2014 | Meeting abstract
Smoking alters the antigenicity and infectivity of Porphyromonas gingivalis
Authors:
Iris Zeller, Justin A Hutcherson, Richard J Lamont, Donald R Demuth, Pinar Gumus, Nejat Nizam, Nurcan Buduneli, David A Scott
Published in:
Tobacco Induced Diseases
|
Special Issue 1/2014
Login to get access
Excerpt
Cigarette smokers are more susceptible to periodontal diseases and are more likely to be infected with Porphyromonas gingivalis than non-smokers. Furthermore, smoking is known to alter the expression of P. gingivalis surface components and to compromise IgG generation. The aim of this study was to evaluate if the overall IgG response to P. gingivalis is suppressed in smokers in vivo and if previously established in vitro tobacco-induced phenotypic P. gingivalis changes would be reflected in vivo. …