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Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Identification of distinct polarized macrophage subsets in inflammatory arthritis

Authors: C Ambarus, S Krausz, J Hamann, M H Wenink, TRDJ Radstake, P P Tak, D Baeten

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

The concept of macrophage polarization describes the heterogeneity of activated macrophages under specific microenvironmental conditions. Based on their pro- or anti-inflammatory functions, M1 and M2 macrophages have been described. We aim to assess type 2 inflammation in spondyloarthritis (SpA) versus type 1 inflammation in rheumatoid arthritis (RA). Here, we investigated the expression of cell surface molecules on in vitro differentiated human macrophages. …
Metadata
Title
Identification of distinct polarized macrophage subsets in inflammatory arthritis
Authors
C Ambarus
S Krausz
J Hamann
M H Wenink
TRDJ Radstake
P P Tak
D Baeten
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P39

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