Published in:
Open Access
01-11-2010 | Poster presentation
Role of TRAILR1 and TNFR1A polymorphisms in the susceptibility and pharmacogenetics of rheumatoid arthritis and ankylosing spondylitis patients treated with infliximab
Authors:
M J Morales-Lara, P Conesa-Zamora, V Santaclara, D Torres-Moreno, F Pedrero, J Corral, M Perez-Guillermo, F J Rodríguez-Martínez, E Soriano-Navarro
Published in:
Journal of Translational Medicine
|
Special Issue 1/2010
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Excerpt
Polymorphisms in genes involved in antibody-dependent cellular cytotoxicity and apoptosis have been associated with inter-individual differences in the response to anti-TNF agent infliximab in arthritides. TRAILR1 and TNFR1A are two genes related to the extrinsic pathway of apoptosis. …