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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Monitoring of anti-TNF biological treatments

Authors: A Ruiz del Agua, D Pascual-Salcedo, A Balsa, I Ramos, L Novalbos, S Ramiro, A Martínez, L Simón, D Nagore

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

Many therapeutic proteins, especially chimeric and humanized anti-TNFalpha antibodies, produce an unwanted immune response that can cause secondary failure and infusion reactions [1]. The most widely accepted hypothesis is the neutralization of the therapeutic agents by human anti-drug antibodies (ADA) [2]. …
Literature
1.
Wolbink GJ, Aarden LA, Dijkmans BA: . Curr.Opin.Rheumatol. 2009, 21: 211-215. 10.1097/BOR.0b013e328329ed8b.CrossRefPubMed
2.
Radstake TR, Svenson M, Eijsbouts AM, van den Hoogen FH, Enevold C, van Riel PL, Bendtzen K: . Ann.Rheum.Dis. 2008, 68: 1739-1745. 10.1136/ard.2008.092833.CrossRefPubMed
Metadata
Title
Monitoring of anti-TNF biological treatments
Authors
A Ruiz del Agua
D Pascual-Salcedo
A Balsa
I Ramos
L Novalbos
S Ramiro
A Martínez
L Simón
D Nagore
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P32

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