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Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Painful myositis in the anti-synthetase syndrome with anti-PL12 antibodies

Authors: P Mehta, L Patel, F Roncaroli, M C Pickering, A Brand

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

The idiopathic inflammatory myopathies (IIMs) are characterized by muscle weakness, electromyography (EMG), histological and biochemical features of muscle inflammation. Their classification is evolving due to the myositis-associated autoantibody panel. Anti-aminoacyl-tRNA synthetase (ARS) antibodies are detected in 25-30% patients and define the anti-synthetase syndrome (ASS), a spectrum of interstitial lung disease (ILD), arthritis, fever, Raynaud’s phenomenon and mechanic’s hands. Anti-Jo1 antibodies are most common (20%), whereas anti-PL12 antibodies (alanyl-tRNA synthetase) occur in <3% cases. …
Metadata
Title
Painful myositis in the anti-synthetase syndrome with anti-PL12 antibodies
Authors
P Mehta
L Patel
F Roncaroli
M C Pickering
A Brand
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P52

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