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Open Access 01-12-2010 | Review

Cell cyclins: triggering elements of cancer or not?

Authors: Michael Stamatakos, Victoria Palla, Ioannis Karaiskos, Konstantinos Xiromeritis, Ioannis Alexiou, Ioannis Pateras, Konstantinos Kontzoglou

Published in: World Journal of Surgical Oncology | Issue 1/2010

Abstract

Cyclins are indispensable elements of the cell cycle and derangement of their function can lead to cancer formation. Recent studies have also revealed more mechanisms through which cyclins can express their oncogenic potential. This review focuses on the aberrant expression of G1/S cyclins and especially cyclin D and cyclin E; the pathways through which they lead to tumour formation and their involvement in different types of cancer. These elements indicate the mechanisms that could act as targets for cancer therapy.

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Title: Cell cyclins: triggering elements of cancer or not?
Authors: Michael Stamatakos
Victoria Palla
Ioannis Karaiskos
Konstantinos Xiromeritis
Ioannis Alexiou
Ioannis Pateras
Konstantinos Kontzoglou
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2010
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-8-111

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cell cyclins: triggering elements of cancer or not?

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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