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Open Access 01-12-2006 | Research

Postoperative infections after oesophageal resections: the role of blood transfusions

Authors: Francesca Rovera, Gianlorenzo Dionigi, Luigi Boni, Andrea Imperatori, Alessandra Tabacchi, Giulio Carcano, Mario Diurni, Renzo Dionigi

Published in: World Journal of Surgical Oncology | Issue 1/2006

Abstract

Background

Perioperative blood transfusion carries numerous potential risks concerning the transmission of infective diseases and immunodepression that can facilitate the occurrence of postoperative infectious complications. Explanation of connections between perioperative blood transfusion and postoperative septic complication worldwide is not well documented. Many studies have described a correlation between perioperative blood transfusions and postoperative infections. On the contrary, other studies indicate that factors influencing the need for blood transfusions during surgery have a greater bearing than blood transfusion per se on the occurrence of postoperative complications.

Patients and methods

A prospective study was conducted in our Department on 110 consecutive patients undergoing oesophageal resection for primary cancer, in order to evaluate the incidence of postoperative infections related to perioperative allogenic blood transfusions. For each patient we preoperatively recorded in a computerized data-base several known risk-factors for postoperative infections; in detail we registered the administration of allogenic perioperative blood transfusions (period of administration, number of packages administered).

Results

Among the enrolled 110 patients, 53 (48%) received perioperative blood transfusions: in this group postoperative infections (overall infective complications) occurred in 27 patients. After a multivariate analysis we observed that perioperative blood transfusions significantly affected as an independent variable the development of wound infections (p = 0.02).

Conclusion

Blood transfusions independently affected the incidence of wound infections in patients who underwent oesophageal resection for primary cancer.

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Title: Postoperative infections after oesophageal resections: the role of blood transfusions
Authors: Francesca Rovera
Gianlorenzo Dionigi
Luigi Boni
Andrea Imperatori
Alessandra Tabacchi
Giulio Carcano
Mario Diurni
Renzo Dionigi
Publication date: 01-12-2006
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2006
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-4-80

ACC 2024 Congress

Springer Medicine

Postoperative infections after oesophageal resections: the role of blood transfusions

Abstract

Background

Patients and methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Background

Patients and methods

Results

Conclusion

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