Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2006

Open Access 01-12-2006 | Case report

Solitary pulmonary metastasis from primary melanoma of the oesophagus 5 years after resection of the primary tumor

Authors: Gianlorenzo Dionigi, Francesca Rovera, Luigi Boni, Andrea Imperatori, Renzo Dionigi

Published in: World Journal of Surgical Oncology | Issue 1/2006

Login to get access

Abstract

Background

Primary malignant melanoma of the oesophagus (PMME) is an uncommon tumor. PMME has an aggressive biological behavior, similar to melanomas developed elsewhere in the body. Most patients die from distant metastases, and the overall 5 year survival rate is approximately 4%.

Case presentation

We report a rare case of a solitary pulmonary metastasis found 5 years after curative resection of primary esophageal melanoma. No other sites of metastatic disease were identified. Video-assisted lung wedge resection of the lung nodule was carried out successfully.

Conclusion

This supports the concept that patients with primary melanoma of the oesophagus treated should be carefully followed up.
Appendix
Available only for authorised users
Literature
1.
Cadwell CB: Unusual malignant neoplasm of the esophagus. J Thorac Cardiovasc Surg. 1991, 101: 100-107.
2.
Baur EH: Ein Fall von primarem melanom des esophagus. Arb Geb Pathol Anat Inst Tubingen. 1906, 5: 343-354.
3.
De la Pava S, Nigogosyan G, Pickren JW, Cabrera A: Melanosis of the esophagus. Cancer. 1963, 16: 48-50.CrossRefPubMed
4.
Tateshi R: Argyophil cells and melanocytes in esophageal mucosa. Arch Pathol. 1997, 98: 87-89.
5.
Suzuki H, Nagayo T: Primary tumor of the esophagus other than squamous cell carcinoma: histological classification and statistics in the surgical and autopsied material in Japan. Int Adv Surg Oncol. 1980, 3: 73-109.PubMed
6.
Di Costanzo DP, Urmacher C: Primary malignant melanoma of the esophagus. Am J Surg Pathol. 1987, 11: 46-52.CrossRef
7.
Allen AC, Spitz S: Malignant melanoma: a clinicopathological analysis of the criteria for diagnosis and prognosis. Cancer. 1953, 6: 1-45.CrossRefPubMed
8.
Sabanathan S, Eng J, Pradhan GN: Primary malignant melanoma of the esophagus. Am J Gastroenterol. 1989, 84: 1475-1481.PubMed
9.
Boni L, Benevento A, Dionigi G, Dionigi R: Primary malignant melanoma of the esophagus: a case report. Surg Endosc. 2002, 16: 359-360.CrossRefPubMed
10.
Boni L, Benevento A, Cabrini L, Dionigi G, Dionigi R: Primary melanoma of the esophagus. J Am Coll Surg. 2002, 194: 840-10.1016/S1072-7515(02)01168-7.CrossRefPubMed
11.
Alexander P: Dormant metastases – studies in experimental animals. J Pathol. 1983, 141: 379-383. 10.1002/path.1711410314.CrossRefPubMed
12.
Lin CY: Primary malignant melanoma of the oesophagus presenting with massive melena and hypovolemic shock. ANZ J Surg. 2002, 72: 62-64. 10.1046/j.1445-2197.2002.02297.x.CrossRefPubMed
13.
Chalkiadakis G, Wihlm JM, Morand G, Weill-bousson M, Witz JP: Primary malignant melanoma of the esophagus. Ann Thorac Surg. 1985, 39: 472-475.CrossRefPubMed
14.
Salk D: Technetium-labeled monoclonal antibodies for imaging metastatic melanoma: results of a multicenter clinical study. Semin Oncol. 1988, 15: 608-618.PubMed
15.
Lamki LM, Zukiwski AA, Shanken LJ: Radioimaging of melanoma using 99 mTc-labeled Fab fragment reactive with a high molecular weight melanoma antigen. Cancer Res. 1990, 50: 904-908.
16.
17.
Philip PA, Flaberty L: Treatment of malignant melanoma with interleukin-2. Semin Oncol. 1997, 24: S32-S38.PubMed
18.
Rusciani L, Petraglia S, Alotto M, Calvieri S, Vezzoni G: Postsurgical adjuvant therapy for melanoma Evaluation of a 3-year randomized trial with recombinant interferon-alpha after 3 and 5 years of follow-up. Cancer. 1997, 79: 2354-2360. 10.1002/(SICI)1097-0142(19970615)79:12<2354::AID-CNCR9>3.0.CO;2-L.CrossRefPubMed
19.
Seigler HF, Lucas V, Pickett NJ: DTIC, CCNU, bleomycin and vincristine. Cancer. 1980, 46: 2346-2348.CrossRefPubMed
20.
York RM, Foltz A: Bleomycin, vincristine, lomustine and DTIC chemotherapy for metastatic melanoma. Cancer. 1988, 61: 2183-2186.CrossRefPubMed
21.
Del Prete SA, Maurer LH, O'Donell J, Forcier RJ, LeMarbre P: Combination chemotherapy with cisplatin, carmustine, dacarbazine and tamoxifen in metastatic melanoma. Cancer Treat Rep. 1984, 68: 1403-1405.PubMed
22.
Mc Clay EF, Mastrange MJ, Berd D, Bellet RE: Effective combination chemo/hormonal therapy for malignant melanoma; experience with three consecutive trials. Int J Cancer. 1992, 50: 553-556.CrossRef
23.
Mills SE, Cooper PH: Malignant melanoma of the digestive system. Pathol Annu. 1983, 18: 1-26.PubMed
24.
Saba HI, Cruse CW, Wells KE, Klein CJ, Reintgen DS: Treatment of stage IV malignant melanoma with dacarbazine, carmustine, cisplatin and tamoxifen regimens: a University of South Florida and H. Lee Moffitt Melanoma Center study. Ann Plast Surg. 1992, 28: 65-69.CrossRefPubMed
25.
Jawalekar K, Tretter P: Primary malignant melanoma of the esophagus. J Surg Oncol. 1979, 12: 19-25.CrossRefPubMed
Metadata
Title
Solitary pulmonary metastasis from primary melanoma of the oesophagus 5 years after resection of the primary tumor
Authors
Gianlorenzo Dionigi
Francesca Rovera
Luigi Boni
Andrea Imperatori
Renzo Dionigi
Publication date
01-12-2006
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2006
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-4-22

Other articles of this Issue 1/2006

World Journal of Surgical Oncology 1/2006 Go to the issue

Correspondence

Unexpected death after headache due to a colloid cyst of the third ventricle

Case report

An inguinal hernia sac tumor of extrahepatic cholangiocarcinoma origin

Case report

Post-radiation sarcoma of the neck treated with re-irradiation followed by wide excision

Research

Female urogenital dysfunction following total mesorectal excision for rectal cancer

Case report

Abdominal wall implantation of hepatocellular carcinoma

Research

"Resurrection of clinical efficacy" after resistance to endocrine therapy in metastatic breast cancer