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Open Access 01-12-2014 | Case report

Retroperitoneal Castleman’s disease: advocating a multidisciplinary approach for a rare clinical entity

Authors: Austin D Williams, Adriana Sanchez, Jun Steve Hou, Rene Rothstein Rubin, Mark E Hysell, Blake D Babcock, Mohammad F Shaikh, Michael S Weingarten, Wilbur B Bowne

Published in: World Journal of Surgical Oncology | Issue 1/2014

Abstract

Background

Castleman’s disease is a rare and poorly understood disease entity that may resemble more common conditions and represents a clinical challenge to the treating surgeon.

Case presentation

In this report, we describe a case of a 61-year-old Caucasian woman with a symptomatic retroperitoneal mass. The specimen obtained from her resection contained a protuberant encapsulated mass, exhibiting microscopic features consistent with localized, unicentric Castleman’s disease. These characteristics included architectural features and immunohistochemical findings consistent with the hyaline vascular variant of Castleman’s disease.

Conclusion

We report a very rare case of a retroperitoneal hyaline vascular type of Castleman’s disease. We discuss the diagnostic dilemma Castleman’s disease may present to the surgeon, with an emphasis on multidisciplinary management of these patients. We also review current data on pathogenesis, treatment and outcomes.

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Title: Retroperitoneal Castleman’s disease: advocating a multidisciplinary approach for a rare clinical entity
Authors: Austin D Williams
Adriana Sanchez
Jun Steve Hou
Rene Rothstein Rubin
Mark E Hysell
Blake D Babcock
Mohammad F Shaikh
Michael S Weingarten
Wilbur B Bowne
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-12-30

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Retroperitoneal Castleman’s disease: advocating a multidisciplinary approach for a rare clinical entity

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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