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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2012

Open Access 01-12-2012 | Case report

Case report: lymphoepithelial-like carcinoma of the lung-a chronic disease?

Authors: Joelle FS Wong, Melissa CC Teo

Published in: World Journal of Surgical Oncology | Issue 1/2012

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Abstract

This is a case of metastatic lung cancer of the lymphoepithelial-like carcinoma (LELC) variant who first presented with symptomatic brain metastasis. The patient underwent local and systemic treatment for metastatic disease with good clinical outcome. The patient was disease free for four years then she had primary lung recurrence which was surgically resected. She underwent a second course of chemotherapy with saw her through another two years of disease free period. A recurrence of the cancer was detected intra-abdominally on the seventh year of diagnosis. This was treated again with surgical resection and another course of chemotherapy.
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Literature
1.
Williamson SR, Zhang S, Lopez-Beltran A, Shah RB, Montironi R, Tan PH, Wang M, Baldridge LA, MacLennan GT, Cheng L: Lymphoepithelioma-like carcinoma of the urinary bladder: clinicopathologic, immunohistochemical, and molecular features. Am J Surg Pathol. 2011, 35 (4): 474-483. 10.1097/PAS.0b013e31820f709e.CrossRefPubMed
2.
Blasi MA, Ventura L, Laguardia M, Tiberti AC, Sammarco MG, Balestrazzi E: Lymphoepithelioma-like carcinoma involving the lacrimal gland and infiltrating the eyelids. Eur J Ophthalmol. 2010, 21 (3): 320-323.CrossRef
3.
Brun Jean-Luc MD, Randriambelomanana , Joseph MD: Cher International Journal of Gynecological Pathology: Pathology of the Upper Genital Tract: Case Reports - Lymphoepithelioma-like Carcinoma of the Ovary. A Case Report and Review of the Literature. 2010, 29 (5): 427-431.
4.
Tseng CJ, Pao CC, Tseng LH, Chang CT, Lai CH, Soong YK, Hsueh S, Jyu-Jen H: Lymphoepithelioma-like carcinoma of the uterine cervix: association with Epstein-Barr virus and human papillomavirus. Cancer. 1997, 80 (1): 91-97. 10.1002/(SICI)1097-0142(19970701)80:1<91::AID-CNCR12>3.0.CO;2-A.CrossRefPubMed
5.
Aoki R, Mitsui H, Harada K, Kawamura T, Shibagaki N, Tsukamoto K, Murata S, Shimada S: A case of lymphoepithelioma-like carcinoma of the skin associated with Epstein-Barr virus infection. J Am Acad Dermatol. 2010, 62 (4): 681-684. 10.1016/j.jaad.2008.07.024.CrossRefPubMed
6.
Begin LR, Eskandari J, Joncas J, Panasci L: Epstein Barr virus related lymphoepithelioma-like carcinoma of lung. J Surg Oncol. 1987, 36: 280-283. 10.1002/jso.2930360413.CrossRefPubMed
7.
Higashiyama M, Doi O, Kodama K: Lymphoepithelioma-like carcinoma of lungs: Analysis of 2 cases for Epstein-Barr virus infection. Human Pathol. 1995, 26: 1278-1282. 10.1016/0046-8177(95)90206-6.CrossRef
8.
Pittaluga S, Wong MP, Chung LP: Clonal Epstein-Barr virus in lymphoepithelioma-like carcinoma of the lung. Am J Surg Pathol. 1993, 17: 678-682. 10.1097/00000478-199307000-00004.CrossRefPubMed
9.
Iezzoni JC, Gaffey MJ, Weiss LM: The role of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the lung. Cancer. 1995, 76: 413-422. 10.1002/1097-0142(19950801)76:3<413::AID-CNCR2820760311>3.0.CO;2-X.CrossRef
10.
Ho JC, Lam WK, Ooi GC: Lymphoepithelioma-like carcinoma of the lung in a patient with silicosis. European Respiratory Journal. 2003, 22 (2): 383-386. 10.1183/09031936.03.00115102.CrossRefPubMed
11.
Hessel PA, Gamble JF, Gee JB: Silica, silicosis and lung cancer : a response to a recent working group report. J Occup Environ Med. 2000, 704-720.
12.
Pairon JC, Brochard P, Jaurand MC, Bignon J: Silica and lung cancer: a controversial issue. Eur Respir J. 1991, 4: 730-744.PubMed
13.
NIOSH Hazard Review Health effects of Occupational exposure to Respirable Crystalline Silica. Department of Health and Human Services. National Institute for Occupational Safety and Health.April 2002:
14.
Hoxworth JM: et al. Lymphoepithelioma-like carcinoma of the Lung: Radiologic Features of an uncommon primary pulmonary neoplasm. AJR: 186 May 2006:
15.
Chan JK, Hui PK, Tsang WY: Primary lymphoepithelioma-like carcinoma of the lung: a clinicopathologic study of 11 cases. Cancer. 1995, 76: 413-422. 10.1002/1097-0142(19950801)76:3<413::AID-CNCR2820760311>3.0.CO;2-X.CrossRefPubMed
16.
Ooi C, Ho M, Khong L, Wong P, Lam K, Tsang T: Computed tomography characteristics of advanced primary pulmonary lympheepithelioma-like carcinoma. Eur Radiol. 2003, 13: 522-526.PubMed
17.
Yi Chin A: Tissue Characterization of Solitary Pulmonary Nodule: Comparative Study Between Helical Dynamic CT and Integrated PET/CT. The J of Nucl Med. 2006, 47: 443-450.
18.
Cappabianca S: Preliminary study on the correlation between grading and histology of solitary pulmonary nodules and contrast enhancement and [18F]fluorodeoxyglucose standardized uptake value after evaluation by dynamic multiphase CT and PET/CT. 2012, group.bmj.com
19.
Cheng CS, Yeung WH, Kwok WK, Kwan WH: Lymphoepithelial-like Carcinoma of the Lung. J HK Coll Radiol. 2002, 5: 47-49.CrossRef
20.
Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y: The new World Health Organization Classification of Lung Tumor. Eur Respir J. 2001, 18: 1059-1068. 10.1183/09031936.01.00275301.CrossRefPubMed
21.
NCCN clinical practice guidelines in oncology NSCLC. V3.2011. National Comprehensive Cancer Network ®
22.
Han AJ, Xiong M, Gu Y, Lin S, Xiong M: Lymphoepithelioma-like carcinoma of the lung with a better prognosis. Am J Clin Pathol. 2001, 115: 841-850. 10.1309/BUAN-BGFW-69U9-C3H8.CrossRefPubMed
23.
Frank MW, Shields TW, Joob AW: Lymphoepithelioma like carcinoma of the lung. Ann Thorac Surg. 1997, 64: 1162-1164. 10.1016/S0003-4975(97)00808-4.CrossRefPubMed
24.
Chen FF, Yan JJ, Lai WW, Jin YT, Su IJ: Epstein-Barr virus-associated nonsmall cell lung carcinoma: undifferentiated “lymphoepithelioma-like” carcinoma as a distinct entity with better prognosis. Cancer. 1998, 82 (12): 2334-2342. 10.1002/(SICI)1097-0142(19980615)82:12<2334::AID-CNCR6>3.0.CO;2-S.CrossRefPubMed
Metadata
Title
Case report: lymphoepithelial-like carcinoma of the lung-a chronic disease?
Authors
Joelle FS Wong
Melissa CC Teo
Publication date
01-12-2012
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2012
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-10-91

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