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Published in: BMC Public Health 1/2014

Open Access 01-12-2014 | Research article

Lower vitamin D status is more common among Saudi adults with diabetes mellitus type 1 than in non-diabetics

Authors: Nasser M Al-Daghri, Omar S Al-Attas, Majed S Alokail, Khalid M Alkharfy, Sobhy M Yakout, Naji J Aljohani, Hanan Al Fawaz, Abdulrahman SM Al-Ajlan, Eman S Sheshah, Mansour Al-Yousef, Mohammad Alharbi

Published in: BMC Public Health | Issue 1/2014

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Abstract

Background

Vitamin D deficiency is an increasingly recognized comorbidity in patients with type 1 diabetes mellitus (DMT1), suggesting that vitamin D deficiency might play a role in DMT1. We aimed to determine and compare the vitamin D status of Saudi adults with and without DMT1.

Methods

A total of 60 Saudi adults with DMT1 from the Diabetes Clinics and 60 non-DM, healthy controls were included in the study. The mean age for those with DMT1 was 25.9 ± 16.1 years versus 36.7 ± 3.6 years among the controls. We measured serum 25-hydroxy vitamin D (25OHD), calcium, cholesterol, blood glucose, HDL, and triglycerides and compared the results between the DMT1 group and control subjects.

Results

Both the DMT1 and healthy groups had vitamin D deficiency. The mean levels of 25OHD were significantly lower in the DMT1 adults than in the controls (28.1 ± 1.4 nmol/L versus 33.4 ± 1.6 nmol/L). In the DMT1 adults, 66.7% were mildly, 31.7% moderately, and 3.3% severely vitamin D deficient as compared with 41.7% (mildly), 31.7% (moderately), and 5% (severely) in the control group. Overall, 100% of the DMT1 adults and 78% of the healthy children were vitamin D deficient.

Conclusion

The prevalence of vitamin D deficiency among DMT1 adults was relatively high. Therefore, screening for vitamin D deficiency and supplementation for this population should be warranted.
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Metadata
Title
Lower vitamin D status is more common among Saudi adults with diabetes mellitus type 1 than in non-diabetics
Authors
Nasser M Al-Daghri
Omar S Al-Attas
Majed S Alokail
Khalid M Alkharfy
Sobhy M Yakout
Naji J Aljohani
Hanan Al Fawaz
Abdulrahman SM Al-Ajlan
Eman S Sheshah
Mansour Al-Yousef
Mohammad Alharbi
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2014
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-14-153

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