Skip to main content
Top
Published in: BMC Public Health 1/2014

Open Access 01-12-2014 | Research article

Adherence to treatment to help quit smoking: effects of task performance and coping with withdrawal symptoms

Authors: Francisca López-Torrecillas, Maria Mar Rueda, Eva María López-Quirantes, Javier Machado Santiago, Reyes Rodríguez Tapioles

Published in: BMC Public Health | Issue 1/2014

Login to get access

Abstract

Background

Currently the combined cognitive-behavioral and pharmacological treatment is the best option to quit smoking, although success rates remain moderate. This study aimed to identify predictors of continuous abstinence in an assisted smoking cessation program using combined treatment. In particular, we analyzed the effects of socio-demographic, smoking-, and treatment-related variables. In addition, we analyzed the effect of several risk factors on abstinence, and estimated a model of risk for smoking relapse.

Methods

Participants were 125 workers at the University of Granada (50 males), with an average age of 46.91 years (SD = 8.15). They were recruited between 2009 and 2013 at an occupational health clinic providing smoking cessation treatment. Baseline measures included socio-demographic data, preferred brand of cigarettes, number of years smoking, use of alcohol and/or tranquilizers, past attempts to quit, Fargerström Test for Nicotine Dependence, Smoking Processes of Change Scale, and Coping with Withdrawal Symptoms Interview. Participants were invited to a face-to-face assessment of smoking abstinence using self-report and cooximetry hemoglobin measures at 3, 6, and 12 months follow-up. The main outcome was smoking status coded as “relapse” versus “abstinence” at each follow-up. Kaplan-Meier survival analysis was performed to estimate the probability of continued abstinence during 12 months and log-rank tests were used to analyze differences in continued abstinence as a function of socio-demographic, smoking-, and treatment-related variables. Cox regression was used to analyze the simultaneous effect of several risk factors on abstinence.

Results

Using alcohol and/or tranquilizers was related to shorter abstinence. Physical exercise, the number of treatment sessions, performance of treatment tasks, and coping with withdrawal symptoms were related to prolonged abstinence. In particular, failure to perform the treatment tasks tripled the risk of relapse, while lack of coping doubled it.

Conclusions

Our results show that physical exercise, performance of treatment-related tasks, and effective coping with withdrawal symptoms can prolong abstinence from smoking. Programs designed to help quit smoking can benefit from the inclusion of these factors.
Appendix
Available only for authorised users
Literature
1.
go back to reference Patwardhan P, McMillen R, Winickoff JP: Consumer perceptions of the sale of tobacco products in pharmacies and grocery stores among U.S. adults. BMC Res Notes. 2013, 6: 261-268. 10.1186/1756-0500-6-261. doi:10.1186/1756-0500-6-261CrossRefPubMedPubMedCentral Patwardhan P, McMillen R, Winickoff JP: Consumer perceptions of the sale of tobacco products in pharmacies and grocery stores among U.S. adults. BMC Res Notes. 2013, 6: 261-268. 10.1186/1756-0500-6-261. doi:10.1186/1756-0500-6-261CrossRefPubMedPubMedCentral
3.
go back to reference Japuntich SJ, Piper ME, Leventhal AM, Bolt DM, Baker TB: The effect of five smoking cessation pharmacotherapies on smoking cessation milestones. J Consult Clin Psychol. 2011, 79 (1): 34-42. doi:10.1037/a0022154CrossRefPubMedPubMedCentral Japuntich SJ, Piper ME, Leventhal AM, Bolt DM, Baker TB: The effect of five smoking cessation pharmacotherapies on smoking cessation milestones. J Consult Clin Psychol. 2011, 79 (1): 34-42. doi:10.1037/a0022154CrossRefPubMedPubMedCentral
4.
go back to reference Secades-Villa R, Alonso-Perez F, Garcia-Rodriguez O, Fernandez-Hermida JR: Effectiveness of three intensities of smoking cessation treatment in primary care. Percept Mot Skills. 2009, 105: 747-758. doi:10.2466/pr0.105.3.747-758 Secades-Villa R, Alonso-Perez F, Garcia-Rodriguez O, Fernandez-Hermida JR: Effectiveness of three intensities of smoking cessation treatment in primary care. Percept Mot Skills. 2009, 105: 747-758. doi:10.2466/pr0.105.3.747-758
5.
go back to reference Shiffman S, Brockwell SE, Pillitteri JL: Individual differences in adoption of treatment for smoking cessation: demographic and smoking history characteristics. Drug Alcohol Depend. 2008, 93: 121-131. 10.1016/j.drugalcdep.2007.09.005. doi:10.1016/j.drugalcdep.2007.09.005CrossRefPubMed Shiffman S, Brockwell SE, Pillitteri JL: Individual differences in adoption of treatment for smoking cessation: demographic and smoking history characteristics. Drug Alcohol Depend. 2008, 93: 121-131. 10.1016/j.drugalcdep.2007.09.005. doi:10.1016/j.drugalcdep.2007.09.005CrossRefPubMed
6.
go back to reference Cahill K, Stevens S, Perera R, Lancaster T: Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2013, 31 (5): CD009329-doi:10.1002/14651858.CD009329.pub2 Cahill K, Stevens S, Perera R, Lancaster T: Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2013, 31 (5): CD009329-doi:10.1002/14651858.CD009329.pub2
7.
go back to reference Ortega F, Vellisco A, Márquez E, López-Campos JL, Rodríguez A, de los Ángeles Sánchez M, Barrot E, Cejudo P: Effectiveness of a cognitive orientation program with and without nicotine replacement therapy in stopping smoking in hospitalized patients. Arch Bronconeumol. 2011, 47 (1): 3-9. doi:10.1016/j.arbres.2010.07.007CrossRefPubMed Ortega F, Vellisco A, Márquez E, López-Campos JL, Rodríguez A, de los Ángeles Sánchez M, Barrot E, Cejudo P: Effectiveness of a cognitive orientation program with and without nicotine replacement therapy in stopping smoking in hospitalized patients. Arch Bronconeumol. 2011, 47 (1): 3-9. doi:10.1016/j.arbres.2010.07.007CrossRefPubMed
8.
go back to reference Rigotti NA, Clair C, Munafò MR, Stead LF: Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev. 2012, 16 (5): CD001837-doi: 10.1002/14651858.CD001837.pub3 Rigotti NA, Clair C, Munafò MR, Stead LF: Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev. 2012, 16 (5): CD001837-doi: 10.1002/14651858.CD001837.pub3
9.
go back to reference Agaku IT, King BA, Dube SR, EIS officer, CDC: Current cigarette smoking among adults - United States, 2005-2012. Morb Mortal Wkly Rep. 2014, 63 (2): 29-34. PubMed PMID: 24430098 Agaku IT, King BA, Dube SR, EIS officer, CDC: Current cigarette smoking among adults - United States, 2005-2012. Morb Mortal Wkly Rep. 2014, 63 (2): 29-34. PubMed PMID: 24430098
10.
go back to reference Bala MM, Strzeszynski L, Topor-Madry R, Cahill K: Mass media interventions for smoking cessation in adults. Cochrane Database Syst Rev. 2013, 6 (6): CD004704-doi: 10.1002/14651858.CD004704.pub3PubMed Bala MM, Strzeszynski L, Topor-Madry R, Cahill K: Mass media interventions for smoking cessation in adults. Cochrane Database Syst Rev. 2013, 6 (6): CD004704-doi: 10.1002/14651858.CD004704.pub3PubMed
11.
go back to reference Centers for Disease Control and Prevention (CDC): Cigarette smoking among adults--United States, 2007. MMWR Morb Mortal Wkly Rep. 2008, 57 (45): 1221-1226. PMID: 19008790 Centers for Disease Control and Prevention (CDC): Cigarette smoking among adults--United States, 2007. MMWR Morb Mortal Wkly Rep. 2008, 57 (45): 1221-1226. PMID: 19008790
12.
go back to reference Becoña E, Vázquez MI, Míguez MC, Fernández del Río E, López-Durán A, Martínez U, Piñeiro B: Smoking habit profile and health-related quality of life. Psicothema. 2013, 25 (4): 421-426. doi: 10.7334/psicothema2013.73PubMed Becoña E, Vázquez MI, Míguez MC, Fernández del Río E, López-Durán A, Martínez U, Piñeiro B: Smoking habit profile and health-related quality of life. Psicothema. 2013, 25 (4): 421-426. doi: 10.7334/psicothema2013.73PubMed
13.
go back to reference Burgess DJ, Fu SS, Noorbaloochi S, Clothier BA, Ricards J, Widome R, van Ryn M: Employment, gender, and smoking cessation outcomes in low-income smokers using nicotine replacement therapy. Nicotine Tob Res. 2009, 11 (12): 1439-1447. 10.1093/ntr/ntp158. doi:10.1093/ntr/ntp158CrossRefPubMed Burgess DJ, Fu SS, Noorbaloochi S, Clothier BA, Ricards J, Widome R, van Ryn M: Employment, gender, and smoking cessation outcomes in low-income smokers using nicotine replacement therapy. Nicotine Tob Res. 2009, 11 (12): 1439-1447. 10.1093/ntr/ntp158. doi:10.1093/ntr/ntp158CrossRefPubMed
14.
go back to reference Ghani WM, Razak IA, Yang YH, Talib NA, Ikeda N, Axell T, Gupta PC, Handa Y, Abdullah N, Zain RB: Factors affecting commencement and cessation of smoking behaviour in Malaysian adults. BMC Public Health. 2012, 19 (12): 207-219. doi:10.1186/1471-2458-12-207CrossRef Ghani WM, Razak IA, Yang YH, Talib NA, Ikeda N, Axell T, Gupta PC, Handa Y, Abdullah N, Zain RB: Factors affecting commencement and cessation of smoking behaviour in Malaysian adults. BMC Public Health. 2012, 19 (12): 207-219. doi:10.1186/1471-2458-12-207CrossRef
15.
go back to reference Hagimoto A, Nakamura M, Morita T, Masui S, Oshima A: Smoking cessation patterns and predictors of quitting smoking among the Japanese general population: a 1-year follow-up study. Addiction. 2010, 105 (1): 164-173. 10.1111/j.1360-0443.2009.02735.x. doi:10.1111/j.1360-0443.2009.02735.xCrossRefPubMed Hagimoto A, Nakamura M, Morita T, Masui S, Oshima A: Smoking cessation patterns and predictors of quitting smoking among the Japanese general population: a 1-year follow-up study. Addiction. 2010, 105 (1): 164-173. 10.1111/j.1360-0443.2009.02735.x. doi:10.1111/j.1360-0443.2009.02735.xCrossRefPubMed
17.
go back to reference Nerín I, Novella P, Beamonte A, Gargallo P, Jiménez-Muro A, Marqueta A: Results of smoking cessation therapy in a specialist unit. Arch Bronconeumol. 2007, 43 (12): 669-673. 10.1157/13112965. doi:10.1157/13112965CrossRefPubMed Nerín I, Novella P, Beamonte A, Gargallo P, Jiménez-Muro A, Marqueta A: Results of smoking cessation therapy in a specialist unit. Arch Bronconeumol. 2007, 43 (12): 669-673. 10.1157/13112965. doi:10.1157/13112965CrossRefPubMed
18.
go back to reference Nordstrom BL, Kinnunen T, Utman CH, Krall EA, Vokonas PS, Garvey AJ: Predictors of continued smoking over 25 years of follow-up in the normative aging study. Am J Public Health. 2000, 90 (3): 404-406. doi:10.1111/j.1758-5872.2012.00175.xCrossRefPubMedPubMedCentral Nordstrom BL, Kinnunen T, Utman CH, Krall EA, Vokonas PS, Garvey AJ: Predictors of continued smoking over 25 years of follow-up in the normative aging study. Am J Public Health. 2000, 90 (3): 404-406. doi:10.1111/j.1758-5872.2012.00175.xCrossRefPubMedPubMedCentral
19.
go back to reference Ramos M, Ripoll J, Estrades T, Socias I, Fe A, Duro R, González MJ, Servera M: Effectiveness of intensive group and individual interventions for smoking cessation in primary health care settings: a randomized trial. BMC Public Health. 2010, 23 (10): 89-99. doi:10.1186/1471-2458-10-89CrossRef Ramos M, Ripoll J, Estrades T, Socias I, Fe A, Duro R, González MJ, Servera M: Effectiveness of intensive group and individual interventions for smoking cessation in primary health care settings: a randomized trial. BMC Public Health. 2010, 23 (10): 89-99. doi:10.1186/1471-2458-10-89CrossRef
20.
go back to reference Shiffman S: Reflections on smoking relapse research. Drug Alcohol Rev. 2006, 25 (1): 15-20. 10.1080/09595230500459479. PubMed PMID: 16492573CrossRefPubMed Shiffman S: Reflections on smoking relapse research. Drug Alcohol Rev. 2006, 25 (1): 15-20. 10.1080/09595230500459479. PubMed PMID: 16492573CrossRefPubMed
22.
go back to reference Balmford J, Borland R, Hammond D, Cummings KM: Adherence to and reasons for premature discontinuation from stop-smoking medications: data from the ITC Four-Country Survey. Nicotine Tob Res. 2011, 13 (2): 94-102. 10.1093/ntr/ntq215. doi:10.1093/ntr/ntq215CrossRefPubMed Balmford J, Borland R, Hammond D, Cummings KM: Adherence to and reasons for premature discontinuation from stop-smoking medications: data from the ITC Four-Country Survey. Nicotine Tob Res. 2011, 13 (2): 94-102. 10.1093/ntr/ntq215. doi:10.1093/ntr/ntq215CrossRefPubMed
23.
go back to reference Prochaska JJ, Hall SM, Humfleet G, Munoz RF, Reus V, Gorecki J, Hu D: Physical activity as a strategy for maintaining tobacco abstinence: a randomized trial. Prev Med. 2008, 47 (2): 215-220. 10.1016/j.ypmed.2008.05.006. doi:10.1016/j.ypmed.2008.05.006CrossRefPubMedPubMedCentral Prochaska JJ, Hall SM, Humfleet G, Munoz RF, Reus V, Gorecki J, Hu D: Physical activity as a strategy for maintaining tobacco abstinence: a randomized trial. Prev Med. 2008, 47 (2): 215-220. 10.1016/j.ypmed.2008.05.006. doi:10.1016/j.ypmed.2008.05.006CrossRefPubMedPubMedCentral
24.
go back to reference Scioli ER, Biller H, Rossi J, Riebe D: Personal motivation, exercise and smoking behaviors among young adults. Behav Med. 2009, 35 (2): 57-64. 10.3200/BMED.35.2.57-66. doi:10.3200/BMED. 35.2.57-66CrossRefPubMed Scioli ER, Biller H, Rossi J, Riebe D: Personal motivation, exercise and smoking behaviors among young adults. Behav Med. 2009, 35 (2): 57-64. 10.3200/BMED.35.2.57-66. doi:10.3200/BMED. 35.2.57-66CrossRefPubMed
25.
go back to reference Zhang L, Samet J, Caffo B, Bankman I, Punjabi NM: Power spectral analysis of EEG activity during sleep in cigarette smokers. Chest. 2008, 133 (2): 427-432. 10.1378/chest.07-1190. PubMed PMID: 17925420CrossRefPubMed Zhang L, Samet J, Caffo B, Bankman I, Punjabi NM: Power spectral analysis of EEG activity during sleep in cigarette smokers. Chest. 2008, 133 (2): 427-432. 10.1378/chest.07-1190. PubMed PMID: 17925420CrossRefPubMed
26.
go back to reference Roberts V, Maddison R, Simpson C, Bullen C, Prapavessis H: The acute effects of exercise on cigarette cravings, withdrawal symptoms, affect, and smoking behaviour: systematic review update and meta-analysis. Psychopharmacology. 2012, 222 (1): 1-15. 10.1007/s00213-012-2731-z. doi:10.1007/s00213-012-2731-zCrossRefPubMed Roberts V, Maddison R, Simpson C, Bullen C, Prapavessis H: The acute effects of exercise on cigarette cravings, withdrawal symptoms, affect, and smoking behaviour: systematic review update and meta-analysis. Psychopharmacology. 2012, 222 (1): 1-15. 10.1007/s00213-012-2731-z. doi:10.1007/s00213-012-2731-zCrossRefPubMed
27.
go back to reference Heckman BW, Kovacs MA, Marquinez NS, Meltzer LR, Tsambarlis ME, Drobes DJ, Brandon TH: Influence of affective manipulations on cigarette craving: a meta-analysis. Addiction. 2013, 108 (12): 2068-2078. 10.1111/add.12284. doi:10.1111/add.12284CrossRefPubMed Heckman BW, Kovacs MA, Marquinez NS, Meltzer LR, Tsambarlis ME, Drobes DJ, Brandon TH: Influence of affective manipulations on cigarette craving: a meta-analysis. Addiction. 2013, 108 (12): 2068-2078. 10.1111/add.12284. doi:10.1111/add.12284CrossRefPubMed
30.
go back to reference Hughes JR, Keely JP, Niaura RS, Ossip-Klein DJ, Richmond RL, Swan GE: Measures of abstinence in clinical trials: issues and recommendations. Nicotine Tob Res. 2003, 5: 13-25. 10.1093/ntr/5.1.13.CrossRefPubMed Hughes JR, Keely JP, Niaura RS, Ossip-Klein DJ, Richmond RL, Swan GE: Measures of abstinence in clinical trials: issues and recommendations. Nicotine Tob Res. 2003, 5: 13-25. 10.1093/ntr/5.1.13.CrossRefPubMed
31.
go back to reference Fu SS, van Ryn M, Sherman SE, Burgess DJ, Noorbaloochi S, Clothier B, Joseph AM: Population-based tobacco treatment: study design of a randomized controlled trial. BMC Public Health. 2012, 6: 12-159. doi:10.1186/1471-2458-12-159 Fu SS, van Ryn M, Sherman SE, Burgess DJ, Noorbaloochi S, Clothier B, Joseph AM: Population-based tobacco treatment: study design of a randomized controlled trial. BMC Public Health. 2012, 6: 12-159. doi:10.1186/1471-2458-12-159
32.
go back to reference Lindqvist H, Forsberg LG, Forsberg L, Rosendahl I, Enebrink P, Helgason AR: Motivational interviewing in an ordinary clinical setting: a controlled clinical trial at the Swedish National Tobacco Quitline. Addict Behav. 2013, 38 (7): 2321-2324. 10.1016/j.addbeh.2013.03.002. doi:10.1016/j.addbeh.2013.03.002CrossRefPubMed Lindqvist H, Forsberg LG, Forsberg L, Rosendahl I, Enebrink P, Helgason AR: Motivational interviewing in an ordinary clinical setting: a controlled clinical trial at the Swedish National Tobacco Quitline. Addict Behav. 2013, 38 (7): 2321-2324. 10.1016/j.addbeh.2013.03.002. doi:10.1016/j.addbeh.2013.03.002CrossRefPubMed
33.
go back to reference López-Torrecillas F: PhD thesis doctoral. Estrés, afrontamiento, variables de personalidad y consumo de drogas. 1995, Departamento de Personalidad, Evaluación y Tratamiento Psicológico: Universidad de Granada López-Torrecillas F: PhD thesis doctoral. Estrés, afrontamiento, variables de personalidad y consumo de drogas. 1995, Departamento de Personalidad, Evaluación y Tratamiento Psicológico: Universidad de Granada
34.
go back to reference Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom K: The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J of Addic. 1991, 86: 1119-1127. 10.1111/j.1360-0443.1991.tb01879.x.CrossRef Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom K: The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J of Addic. 1991, 86: 1119-1127. 10.1111/j.1360-0443.1991.tb01879.x.CrossRef
35.
go back to reference De Leon J, Becoña E, Gurpegui M, González-Pinto A, Diaz FJ: The association between high nicotine dependence and severe mental illness may be consistent across countries. J Clin Psychiatry. 2002, 63: 812-816. 10.4088/JCP.v63n0911.CrossRefPubMed De Leon J, Becoña E, Gurpegui M, González-Pinto A, Diaz FJ: The association between high nicotine dependence and severe mental illness may be consistent across countries. J Clin Psychiatry. 2002, 63: 812-816. 10.4088/JCP.v63n0911.CrossRefPubMed
36.
go back to reference Becoña E, Vázquez FL: The Fagerström Test for Nicotine Dependence in a Spanish sample. Psychol Rep. 1998, 83: 1455-1458. 10.2466/pr0.1998.83.3f.1455.CrossRefPubMed Becoña E, Vázquez FL: The Fagerström Test for Nicotine Dependence in a Spanish sample. Psychol Rep. 1998, 83: 1455-1458. 10.2466/pr0.1998.83.3f.1455.CrossRefPubMed
37.
go back to reference DiClemente CC, Prochaska JO: Processes and stages of change: Coping and competence in smoking behavior change. Coping and Substance Abuse. Edited by: Shiffman S, Wills TA. 1985, New York: Academic Press, 319-343. DiClemente CC, Prochaska JO: Processes and stages of change: Coping and competence in smoking behavior change. Coping and Substance Abuse. Edited by: Shiffman S, Wills TA. 1985, New York: Academic Press, 319-343.
38.
go back to reference Prochaska JO, Velicer WF, DiClemente CC, Fava J: Measuring processes of change: application to the cessation of smoking. J Consult Clin Psychol. 1988, 56: 520-528.CrossRefPubMed Prochaska JO, Velicer WF, DiClemente CC, Fava J: Measuring processes of change: application to the cessation of smoking. J Consult Clin Psychol. 1988, 56: 520-528.CrossRefPubMed
39.
go back to reference Tejero A, Trujols J: El modelo transteorético de Prochaska y Diclemente: un modelo dinámico de cambio en el ámbito de las conductas adictivas. Conductas Adictivas. Edited by: Graña JL. 1994, Madrid: Debate, 3-43 Tejero A, Trujols J: El modelo transteorético de Prochaska y Diclemente: un modelo dinámico de cambio en el ámbito de las conductas adictivas. Conductas Adictivas. Edited by: Graña JL. 1994, Madrid: Debate, 3-43
40.
go back to reference Craig CL, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P: International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003, 35 (8): 1381-1395. 10.1249/01.MSS.0000078924.61453.FB. PMID: 12900694CrossRefPubMed Craig CL, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P: International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003, 35 (8): 1381-1395. 10.1249/01.MSS.0000078924.61453.FB. PMID: 12900694CrossRefPubMed
42.
go back to reference Curry S, Marlatt GA, Peterson AV, Lutton J: Survival analysis and assessment of relapse rates. Assessment of Addictive Behaviors. Edited by: Donevan DM, Marlatt GA. 1988, New York, NY: Guilford Press, 454-473. Curry S, Marlatt GA, Peterson AV, Lutton J: Survival analysis and assessment of relapse rates. Assessment of Addictive Behaviors. Edited by: Donevan DM, Marlatt GA. 1988, New York, NY: Guilford Press, 454-473.
43.
go back to reference Kleinbaum DG, Klein M: Survival Analysis. A Self-learning Text. 2005, New York: Springer Kleinbaum DG, Klein M: Survival Analysis. A Self-learning Text. 2005, New York: Springer
44.
go back to reference Willett JB, Singer JD: Investigating onset, cessation, relapse, and recovery: why you should, and how you can, use discrete-time survival analysis to examine event occurrence. J Consult Clin Psych. 1993, 61: 952-965.CrossRef Willett JB, Singer JD: Investigating onset, cessation, relapse, and recovery: why you should, and how you can, use discrete-time survival analysis to examine event occurrence. J Consult Clin Psych. 1993, 61: 952-965.CrossRef
45.
go back to reference Cox DR: Regression model and life tables. J R Stat Soc. 1972, 34: 187-220. Cox DR: Regression model and life tables. J R Stat Soc. 1972, 34: 187-220.
46.
go back to reference Cox DR, Oakes D: The Analysis of Survival Data. 1984, Londres: Chapman and Hall Cox DR, Oakes D: The Analysis of Survival Data. 1984, Londres: Chapman and Hall
Metadata
Title
Adherence to treatment to help quit smoking: effects of task performance and coping with withdrawal symptoms
Authors
Francisca López-Torrecillas
Maria Mar Rueda
Eva María López-Quirantes
Javier Machado Santiago
Reyes Rodríguez Tapioles
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2014
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-14-1217

Other articles of this Issue 1/2014

BMC Public Health 1/2014 Go to the issue