Published in:
Open Access
01-05-2014 | Oral presentation
Forensic application of phylogenetic analysis – exploration of suspected epidemiological linkage
Authors:
Marina Siljic, Dubravka Salemovic, Djordje Jevtovic, Ivana Pesic-Pavlovic, Sonja Zerjav, Valentina Nikolic, Jovan Ranin, Maja Stanojevic
Published in:
BMC Infectious Diseases
|
Special Issue 4/2014
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Excerpt
Phylogenetic analysis may serve as a valuable tool in assessing the epidemiological relation between viral DNA sequences. In order to increase the likelihood of observing phylogenetic separation of sequences as well as to give strong forensic evidence regarding transmission, phylogenetic analysis needs to be performed on appropriate local control sequences and by sequencing of at least two genetic regions of reasonable length, depending on the gene under investigation. The aim of this study was to explore the suspected epidemiological linkage between DNA sequences isolated from three HIV-1 infected patients by means of phylogenetic analyses. …
