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BMC Infectious Diseases
Published in: BMC Infectious Diseases 3/2014

Open Access 01-05-2014 | Oral presentation

DC SIGNR silencing reduces HIV-1 infection in Dendritic cells

Authors: Omkar Chaudhary, Sanjeev Kumar, Heena Aggarwal, Muzamil A Makhdoomi, Jasbir Singh, Anjali Hazarika, Kalpana Luthra

Published in: BMC Infectious Diseases | Special Issue 3/2014

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Excerpt

Dendritic cells (DCs) capture HIV-1 from periphery via DC SIGN/R receptors and transfer to T cells. It has been reported that siRNA directed against DC SIGN significantly inhibits HIV infection of DCs. In this study, the expression of DC SIGN/R and its role in HIV-1 infectivity of DCs were assessed. …
Metadata
Title
DC SIGNR silencing reduces HIV-1 infection in Dendritic cells
Authors
Omkar Chaudhary
Sanjeev Kumar
Heena Aggarwal
Muzamil A Makhdoomi
Jasbir Singh
Anjali Hazarika
Kalpana Luthra
Publication date
01-05-2014
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue Special Issue 3/2014
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-14-S3-O8

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