Published in:
Open Access
01-05-2014 | ePoster presentation
Production of cross neutralizing single chain fragment variables (scFv) from HIV-1 infected Indian children
Authors:
Sanjeev Kumar, Rajesh Kumar, Muzamil Makhdoomi, Lubina Khan, SS Prakash, Ramachandran Thiruvengadam, Mohit Singla, Rakesh Lodha, SK Kabra, Subrata Sinha, Kalpana Luthra
Published in:
BMC Infectious Diseases
|
Special Issue 3/2014
Login to get access
Excerpt
Monoclonal antibody based vaccines are effective and highly specific in disease targeting. Presently, most of the existing broadly neutralizing antibodies are generated against non subtype c viruses. HIV-1 subtype c accounts for more than 90% of infection in India. The disease progression in children is faster than adults. …