Published in:
Open Access
01-12-2015 | Case report
Noncompaction cardiomyopathy: a substrate for a thromboembolic event
Authors:
Marcelo Dantas Tavares de Melo, José Arimateia Batista de Araújo Filho, Jose Rodrigues Parga Filho, Camila Rocon de Lima, Charles Mady, Roberto Kalil-Filho, Vera Maria Cury Salemi
Published in:
BMC Cardiovascular Disorders
|
Issue 1/2015
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Abstract
Background
Noncompaction cardiomyopathy (NCC) is a rare genetic cardiomyopathy characterized by a thin, compacted epicardial layer and an extensive noncompacted endocardial layer. The clinical manifestations of this disease include ventricular arrhythmia, heart failure, and systemic thromboembolism.
Case presentation
A 43-year-old male was anticoagulated by pulmonary thromboembolism for 1 year when he developed progressive dyspnea. Cardiovascular magnetic resonance imaging showed severe biventricular trabeculation with an ejection fraction of 15%, ratio of maximum noncompacted/compacted diastolic myocardial thickness of 3.2 and the presence of exuberant biventricular apical thrombus.
Conclusion
Still under discussion is the issue of which patients and when they should be anticoagulated. It is generally recommended to those presenting ventricular systolic dysfunction, antecedent of systemic embolism, presence of cardiac thrombus and atrial fibrillation. In clinical practice the patients with NCC and ventricular dysfunction have been given oral anticoagulation, although there are no clinical trials showing the real safety and benefit of this treatment.