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Published in: BMC Cardiovascular Disorders 1/2014

Open Access 01-12-2014 | Research article

Distal end side-to-side anastomoses of sequential vein graft to small target coronary arteries improve intraoperative graft flow

Authors: Haitao Li, Baodong Xie, Chengxiong Gu, Mingxin Gao, Fan Zhang, Jiayang Wang, Longsheng Dai, Yang Yu

Published in: BMC Cardiovascular Disorders | Issue 1/2014

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Abstract

Background

End-to-side anastomoses to connect the distal end of the great saphenous vein (GSV) to small target coronary arteries are commonly performed in sequential coronary artery bypass grafting (CABG). However, the oversize diameter ratio between the GSV and small target vessels at end-to-side anastomoses might induce adverse hemodynamic condition. The purpose of this study was to describe a distal end side-to-side anastomosis technique and retrospectively compare the effect of distal end side-to-side versus end-to-side anastomosis on graft flow characteristics.

Methods

We performed side-to-side anastomoses to connect the distal end of the GSV to small target vessels on 30 patients undergoing off-pump sequential CABG in our hospital between October 2012 and July 2013. Among the 30 patients, end-to-side anastomoses at the distal end of the GSV were initially performed on 14 patients; however, due to poor graft flow, those anastomoses were revised into side-to-side anastomoses. We retrospectively compared the intraoperative graft flow characteristics of the end-to-side versus side-to-side anastomoses in the 14 patients. The patient outcomes were also evaluated.

Results

We found that the side-to-side anastomosis reconstruction improved intraoperative flow and reduced pulsatility index in all the 14 patients significantly. The 16 patients who had the distal end side-to-side anastomoses performed directly also exhibited satisfactory intraoperative graft flow. Three-month postoperative outcomes for all the patients were satisfactory.

Conclusions

Side-to-side anastomosis at the distal end of sequential vein grafts might be a promising strategy to connect small target coronary arteries to the GSV.
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Literature
1.
go back to reference Spivack DE, Kelly P, Gaughan JP, van Bemmelen PS: Mapping of superficial extremity veins: normal diameters and trends in a vascular patient-population. Ultrasound Med Biol. 2012, 38: 190-194. 10.1016/j.ultrasmedbio.2011.11.008.CrossRefPubMed Spivack DE, Kelly P, Gaughan JP, van Bemmelen PS: Mapping of superficial extremity veins: normal diameters and trends in a vascular patient-population. Ultrasound Med Biol. 2012, 38: 190-194. 10.1016/j.ultrasmedbio.2011.11.008.CrossRefPubMed
2.
go back to reference Longest PW, Kleinstreuer C: Particle-hemodynamics modeling of the distal end-to-side femoral bypass: effects of graft caliber and graft-end cut. Med Eng Phys. 2003, 25: 843-58. 10.1016/S1350-4533(03)00124-3.CrossRefPubMed Longest PW, Kleinstreuer C: Particle-hemodynamics modeling of the distal end-to-side femoral bypass: effects of graft caliber and graft-end cut. Med Eng Phys. 2003, 25: 843-58. 10.1016/S1350-4533(03)00124-3.CrossRefPubMed
3.
go back to reference Ghista DN, Kabinejadian F: Coronary artery bypass grafting hemodynamics and anastomosis design: a biomedical engineering review. Bio Medical Engineering On Line. 2013, 12: 129- Ghista DN, Kabinejadian F: Coronary artery bypass grafting hemodynamics and anastomosis design: a biomedical engineering review. Bio Medical Engineering On Line. 2013, 12: 129-
4.
go back to reference Keynton RS1, Evancho MM, Sims RL, Rittgers SE: The effect of graft caliber upon wall shear within in vivo distal vascular anastomoses. J Biomech Eng. 1999, 121: 79-88. 10.1115/1.2798047.CrossRefPubMed Keynton RS1, Evancho MM, Sims RL, Rittgers SE: The effect of graft caliber upon wall shear within in vivo distal vascular anastomoses. J Biomech Eng. 1999, 121: 79-88. 10.1115/1.2798047.CrossRefPubMed
5.
go back to reference Qiao A, Liu Y: Influence of graft-host diameter ratio on the hemodynamics of CABG. Biomed Mater Eng. 2006, 16: 189-201.PubMed Qiao A, Liu Y: Influence of graft-host diameter ratio on the hemodynamics of CABG. Biomed Mater Eng. 2006, 16: 189-201.PubMed
6.
go back to reference Sewell WH: Improved coronary vein graft patency rates with side-to-side anastomoses. Ann Thorac Surg. 1974, 17: 538-544. 10.1016/S0003-4975(10)65695-0.CrossRefPubMed Sewell WH: Improved coronary vein graft patency rates with side-to-side anastomoses. Ann Thorac Surg. 1974, 17: 538-544. 10.1016/S0003-4975(10)65695-0.CrossRefPubMed
7.
go back to reference Bonert M, Myers JG, Fremes S, WILLIAMS J, ETHIER CR: A Numerical Study of Blood Flow in Coronary Artery Bypass Graft Side-to-Side Anastomoses. Ann Biomed Eng. 2002, 30: 599-611.CrossRefPubMed Bonert M, Myers JG, Fremes S, WILLIAMS J, ETHIER CR: A Numerical Study of Blood Flow in Coronary Artery Bypass Graft Side-to-Side Anastomoses. Ann Biomed Eng. 2002, 30: 599-611.CrossRefPubMed
8.
go back to reference Kabinejadian F, Chua LP, Ghista DN, Sankaranarayanan M, Tan YS: A novel coronary artery bypass graft design of sequential anastomoses. Ann Biomed Eng. 2010, 38: 3135-3150. 10.1007/s10439-010-0068-5.CrossRefPubMed Kabinejadian F, Chua LP, Ghista DN, Sankaranarayanan M, Tan YS: A novel coronary artery bypass graft design of sequential anastomoses. Ann Biomed Eng. 2010, 38: 3135-3150. 10.1007/s10439-010-0068-5.CrossRefPubMed
9.
go back to reference Kabinejadian F, Ghista DN: Compliant model of a coupled sequential coronary arterial bypass graft: effects of vessel wall elasticity and non-Newtonian rheology on blood flow regime and hemodynamic parameters distribution. Med Eng Phys. 2012, 34: 860-872. 10.1016/j.medengphy.2011.10.001.CrossRefPubMed Kabinejadian F, Ghista DN: Compliant model of a coupled sequential coronary arterial bypass graft: effects of vessel wall elasticity and non-Newtonian rheology on blood flow regime and hemodynamic parameters distribution. Med Eng Phys. 2012, 34: 860-872. 10.1016/j.medengphy.2011.10.001.CrossRefPubMed
10.
go back to reference Frauenfelder T, Boutsianis E, Schertler T, Husmann L, Leschka S, Poulikakos D, Marincek B, Alkadhi H: Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts. BioMed Eng OnLine. 2007, 6: 35-48. 10.1186/1475-925X-6-35.CrossRefPubMedPubMedCentral Frauenfelder T, Boutsianis E, Schertler T, Husmann L, Leschka S, Poulikakos D, Marincek B, Alkadhi H: Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts. BioMed Eng OnLine. 2007, 6: 35-48. 10.1186/1475-925X-6-35.CrossRefPubMedPubMedCentral
11.
go back to reference Sankaranarayanan M, Ghista DN, Chua LP, Tan YS, Sundaravadivelu K, Kassab GS: Blood flow in an out-of-plane aortag-left coronary sequential bypass graft. Computational Cardiovascular Mechanics: Modeling and Applications in Heart Failure. Edited by: Guccione JM, Kassab GS, Ratcliffe M. 2010, New York: Springer-Verlag, 277-297.CrossRef Sankaranarayanan M, Ghista DN, Chua LP, Tan YS, Sundaravadivelu K, Kassab GS: Blood flow in an out-of-plane aortag-left coronary sequential bypass graft. Computational Cardiovascular Mechanics: Modeling and Applications in Heart Failure. Edited by: Guccione JM, Kassab GS, Ratcliffe M. 2010, New York: Springer-Verlag, 277-297.CrossRef
12.
go back to reference Nabuchi A, Kurata A, Tsukuda K, Tajima H, Kim K: Side-to-Side Anastomosis in Off-Pump Coronary Artery Bypass Grafting. Asian Cardiovasc Thorac Ann. 2000, 8: 394-397. 10.1177/021849230000800427.CrossRef Nabuchi A, Kurata A, Tsukuda K, Tajima H, Kim K: Side-to-Side Anastomosis in Off-Pump Coronary Artery Bypass Grafting. Asian Cardiovasc Thorac Ann. 2000, 8: 394-397. 10.1177/021849230000800427.CrossRef
13.
go back to reference Song MH, Tokuda Y, Ito T: Revival of the side-to-side approach for distal coronary anastomosis. J Cardiothorac Surg. 2007, 2: 2-7. 10.1186/1749-8090-2-2.CrossRefPubMedPubMedCentral Song MH, Tokuda Y, Ito T: Revival of the side-to-side approach for distal coronary anastomosis. J Cardiothorac Surg. 2007, 2: 2-7. 10.1186/1749-8090-2-2.CrossRefPubMedPubMedCentral
14.
go back to reference Kieser TM, FitzGibbon GM, Keon WJ: Sequential coronary bypass grafts. Long-term follow-up. J Thorac Cardiovasc Surg. 1986, 91: 767-772.PubMed Kieser TM, FitzGibbon GM, Keon WJ: Sequential coronary bypass grafts. Long-term follow-up. J Thorac Cardiovasc Surg. 1986, 91: 767-772.PubMed
Metadata
Title
Distal end side-to-side anastomoses of sequential vein graft to small target coronary arteries improve intraoperative graft flow
Authors
Haitao Li
Baodong Xie
Chengxiong Gu
Mingxin Gao
Fan Zhang
Jiayang Wang
Longsheng Dai
Yang Yu
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2014
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/1471-2261-14-65

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