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Published in: BMC Cardiovascular Disorders 1/2012

Open Access 01-12-2012 | Research article

Trends in the use of electrical cardioversion for atrial fibrillation: influence of major trials and guidelines on clinical practice

Authors: Josep M Alegret, Xavier Viñolas, César Romero-Menor, Silvia Pons, Roger Villuendas, Naiara Calvo, Jordi Pérez-Rodon, Xavier Sabaté, and REVERCAT study investigators

Published in: BMC Cardiovascular Disorders | Issue 1/2012

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Abstract

Background

The purpose of the present study was to assess the trends in the use of ECV following published studies that had compared rhythm and rate control strategies on atrial fibrillation (AF), and the recommendations included in the current clinical practice guidelines.

Methods

The REVERCAT is a population-based assessment of the use of electrical cardioversion (ECV) in treating persistent AF in Catalonia (Spain). The initial survey was conducted in 2003 and the follow-up in 2010.

Results

We observed a decrease of 9% in the absolute numbers of ECV performed (436 in 2003 vs. 397 in 2010). This is equivalent to 27% when considering population increases over this period. The patients treated with ECV in 2010 were younger, had a lower prevalence of previous embolism, a higher prevalence of diabetes, and increased body weight. Underlying heart disease factors indicated, in 2010, a higher proportion of NYHA ≥ II and left ventricular ejection fraction <30%. We observed a reduction in the number of ECV performed in 16 of the 27 (67%) participating hospitals. However, there was an increase of 14% in the number of procedures performed in tertiary hospitals, and was related to the increasing use of ECV as a bridge to AF ablation. Considering the initial number of patients treated with ECV, the rate of sinus rhythm at 3 months was almost unchanged (58% in 2003 vs. 57% in 2010; p = 0.9) despite the greater use of biphasic energy in 2010 and a similar prescription of anti-arrhythmic drugs.

Conclusions

Although we observed a decrease in the number of ECVs performed over the 7 year period between the two studies, this technique remains a common option for treating patients with persistent AF. The change in the characteristics of candidate patients did not translate into better outcomes.
Literature
1.
go back to reference Wyse DG, Waldo AL, DiMarco JP, Domanski MJ, Rosenberg Y, Schron EB, Kellen JC, Greene HL, Mickel MC, Dalquist JE, Corley SD: Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med. 2002, 347: 1825-1833.CrossRefPubMed Wyse DG, Waldo AL, DiMarco JP, Domanski MJ, Rosenberg Y, Schron EB, Kellen JC, Greene HL, Mickel MC, Dalquist JE, Corley SD: Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med. 2002, 347: 1825-1833.CrossRefPubMed
2.
go back to reference Van Gelder IC, Hagens VE, Bosker HA, Kingma JH, Kamp O, Kingma T, Kamp O, Kingma T, Said SA, Darmanata JI, Timmermans AJ, Tijssen JG, Crijns HJ: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group. A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation. N Engl J Med. 2002, 347: 1834-1840. 10.1056/NEJMoa021375.CrossRefPubMed Van Gelder IC, Hagens VE, Bosker HA, Kingma JH, Kamp O, Kingma T, Kamp O, Kingma T, Said SA, Darmanata JI, Timmermans AJ, Tijssen JG, Crijns HJ: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group. A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation. N Engl J Med. 2002, 347: 1834-1840. 10.1056/NEJMoa021375.CrossRefPubMed
3.
go back to reference Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, Halperin JL, Le Heuzey JY, Kay GN, Lowe JE, Olsson SB, Prystowsky EN, Tamargo JL, Wann S: 2006 ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation. Eur Heart J. 2006, 27 (16): 1979-2030.CrossRefPubMed Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, Halperin JL, Le Heuzey JY, Kay GN, Lowe JE, Olsson SB, Prystowsky EN, Tamargo JL, Wann S: 2006 ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation. Eur Heart J. 2006, 27 (16): 1979-2030.CrossRefPubMed
4.
go back to reference Talajic M, Khairy P, Levesque S, Connolly SJ, Dorian P, Dubuc M, Guerra PG, Hohnloser SH, Lee KL, Macle L, Nattel S, Pedersen OD, Stevenson LW, Thibault B, Waldo AL, Wyse DG, Roy D: Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol. 2010, 55: 1796-1802. 10.1016/j.jacc.2010.01.023.CrossRefPubMed Talajic M, Khairy P, Levesque S, Connolly SJ, Dorian P, Dubuc M, Guerra PG, Hohnloser SH, Lee KL, Macle L, Nattel S, Pedersen OD, Stevenson LW, Thibault B, Waldo AL, Wyse DG, Roy D: Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol. 2010, 55: 1796-1802. 10.1016/j.jacc.2010.01.023.CrossRefPubMed
5.
go back to reference Fuster V, Rydén LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, Halperin JL, Kay GN, Klein WW, Lévy S, McNamara RL, Prystowsky EN, Wann LS, Wyse DG, Gibbons RJ, Antman EM, Alpert JS, Faxon DP, Fuster V, Gregoratos G, Hiratzka LF, Jacobs AK, Russell RO, Smith SC, Klein WW, Alonso-Garcia A, Blomström-Lundqvist C, de Backer G, Flather M, Hradec J, Oto A, Parkhomenko A, Silber S, Torbicki A: ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. Eur Heart J. 2001, 22: 1852-1923.CrossRefPubMed Fuster V, Rydén LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, Halperin JL, Kay GN, Klein WW, Lévy S, McNamara RL, Prystowsky EN, Wann LS, Wyse DG, Gibbons RJ, Antman EM, Alpert JS, Faxon DP, Fuster V, Gregoratos G, Hiratzka LF, Jacobs AK, Russell RO, Smith SC, Klein WW, Alonso-Garcia A, Blomström-Lundqvist C, de Backer G, Flather M, Hradec J, Oto A, Parkhomenko A, Silber S, Torbicki A: ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. Eur Heart J. 2001, 22: 1852-1923.CrossRefPubMed
6.
go back to reference Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH: Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010, 31: 2369-2429.CrossRefPubMed Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH: Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010, 31: 2369-2429.CrossRefPubMed
7.
go back to reference Wann LS, Curtis AB, January CT, Ellenbogen KA, Lowe JE, Estes NA, Page RL, Ezekowitz MD, Slotwiner DJ, Jackman WM, Stevenson WG, Tracy CM: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Hear Rhythm. 2011, 8: 157-176. 10.1016/j.hrthm.2010.11.047.CrossRef Wann LS, Curtis AB, January CT, Ellenbogen KA, Lowe JE, Estes NA, Page RL, Ezekowitz MD, Slotwiner DJ, Jackman WM, Stevenson WG, Tracy CM: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Hear Rhythm. 2011, 8: 157-176. 10.1016/j.hrthm.2010.11.047.CrossRef
8.
go back to reference Mason PK, Wood MA, Lake D, DiMarco JP: Influence of the randomized trials, AFFIRM and RACE, on the management of atrial fibrillation in two university medical centers. Am J Cardiol. 2005, 95: 1248-1250. 10.1016/j.amjcard.2005.01.059.CrossRefPubMed Mason PK, Wood MA, Lake D, DiMarco JP: Influence of the randomized trials, AFFIRM and RACE, on the management of atrial fibrillation in two university medical centers. Am J Cardiol. 2005, 95: 1248-1250. 10.1016/j.amjcard.2005.01.059.CrossRefPubMed
9.
go back to reference Corley SD, Epstein AE, DiMarco JP, Domanski MJ, Geller N, Greene HL, Josephson RA, Kellen JC, Klein RC, Krahn AD, Mickel M, Mitchell LB, Nelson JD, Rosenberg Y, Schron E, Shemanski L, Waldo AL, Wyse DG, AFFIRM Investigators: Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation. 2004, 109: 1509-1513.CrossRefPubMed Corley SD, Epstein AE, DiMarco JP, Domanski MJ, Geller N, Greene HL, Josephson RA, Kellen JC, Klein RC, Krahn AD, Mickel M, Mitchell LB, Nelson JD, Rosenberg Y, Schron E, Shemanski L, Waldo AL, Wyse DG, AFFIRM Investigators: Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation. 2004, 109: 1509-1513.CrossRefPubMed
10.
go back to reference Klein AL, Grimm RA, Murray RD, Apperson-Hansen C, Asinger RW, Black IW, Davidoff R, Erbel R, Halperin JL, Orsinelli DA, Porter TR, Stoddard MF: Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation. N Engl J Med. 2001, 344: 1411-1420. 10.1056/NEJM200105103441901.CrossRefPubMed Klein AL, Grimm RA, Murray RD, Apperson-Hansen C, Asinger RW, Black IW, Davidoff R, Erbel R, Halperin JL, Orsinelli DA, Porter TR, Stoddard MF: Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation. N Engl J Med. 2001, 344: 1411-1420. 10.1056/NEJM200105103441901.CrossRefPubMed
11.
go back to reference Koster RW, Dorian P, Chapman FW, Schmitt PW, O'Grady SG, Walker RG: A randomized trial comparing monophasic and biphasic waveform shocks for external cardioversion of atrial fibrillation. Am Heart J. 2004, 147: e20-CrossRefPubMed Koster RW, Dorian P, Chapman FW, Schmitt PW, O'Grady SG, Walker RG: A randomized trial comparing monophasic and biphasic waveform shocks for external cardioversion of atrial fibrillation. Am Heart J. 2004, 147: e20-CrossRefPubMed
12.
go back to reference Scholten M, Szili-Torok T, Klootwijk P, Jordaens L: Comparison of monophasic and biphasic shocks for transthoracic cardioversion of atrial fibrillation. Heart. 2003, 89: 1032-1034. 10.1136/heart.89.9.1032.CrossRefPubMedPubMedCentral Scholten M, Szili-Torok T, Klootwijk P, Jordaens L: Comparison of monophasic and biphasic shocks for transthoracic cardioversion of atrial fibrillation. Heart. 2003, 89: 1032-1034. 10.1136/heart.89.9.1032.CrossRefPubMedPubMedCentral
13.
go back to reference Alegret JM, Viñolas X, Sagristá J, Hernandez-Madrid A, Pérez L, Sabaté X, Mont L, Medina A, the REVERSE Study Investigators: Predictors of success and effect of biphasic energy on electrical cardioversion in patients with persistent atrial fibrillation. Europace. 2007, 9: 942-946. 10.1093/europace/eum107.CrossRefPubMed Alegret JM, Viñolas X, Sagristá J, Hernandez-Madrid A, Pérez L, Sabaté X, Mont L, Medina A, the REVERSE Study Investigators: Predictors of success and effect of biphasic energy on electrical cardioversion in patients with persistent atrial fibrillation. Europace. 2007, 9: 942-946. 10.1093/europace/eum107.CrossRefPubMed
14.
go back to reference Guglin M, Maradia K, Chen R, Curtis AB: Relation of obesity to recurrence rate and burden of atrial fibrillation. Am J Cardiol. 2011, 107: 579-582. 10.1016/j.amjcard.2010.10.018.CrossRefPubMed Guglin M, Maradia K, Chen R, Curtis AB: Relation of obesity to recurrence rate and burden of atrial fibrillation. Am J Cardiol. 2011, 107: 579-582. 10.1016/j.amjcard.2010.10.018.CrossRefPubMed
15.
go back to reference Ueng KC, Tsai TP, Yu WC, Tsai CF, Lin MC, Chan KC, Chen CY, Wu DJ, Lin CS, Chen SA: Use of enalapril to facilitate sinus rhythm maintenance after external cardioversion of long-standing persistent atrial fibrillation. Results of a prospective and controlled study. Eur Heart J. 2003, 24: 2090-2098. 10.1016/j.ehj.2003.08.014.CrossRefPubMed Ueng KC, Tsai TP, Yu WC, Tsai CF, Lin MC, Chan KC, Chen CY, Wu DJ, Lin CS, Chen SA: Use of enalapril to facilitate sinus rhythm maintenance after external cardioversion of long-standing persistent atrial fibrillation. Results of a prospective and controlled study. Eur Heart J. 2003, 24: 2090-2098. 10.1016/j.ehj.2003.08.014.CrossRefPubMed
16.
go back to reference Tveit A, Seljeflot I, Grundvold I, Abdelnoor M, Smith P, Arnesen H: Effect of candesartan and various inflammatory markers on maintenance of sinus rhythm after electrical cardioversion for atrial fibrillation. Am J Cardiol. 2007, 99: 1544-1548. 10.1016/j.amjcard.2007.01.030.CrossRefPubMed Tveit A, Seljeflot I, Grundvold I, Abdelnoor M, Smith P, Arnesen H: Effect of candesartan and various inflammatory markers on maintenance of sinus rhythm after electrical cardioversion for atrial fibrillation. Am J Cardiol. 2007, 99: 1544-1548. 10.1016/j.amjcard.2007.01.030.CrossRefPubMed
17.
go back to reference Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Herpen G, Stricker BH, Stijnen T, Lip GY, Witteman JC: Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006, 27: 949-953.CrossRefPubMed Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Herpen G, Stricker BH, Stijnen T, Lip GY, Witteman JC: Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006, 27: 949-953.CrossRefPubMed
18.
go back to reference Naccarelli GV, Varker H, Lin J, Schulman KL: Increasing prevalence of atrial fibrillation and flutter in the United States. Am J Cardiol. 2009, 104: 1534-1539. 10.1016/j.amjcard.2009.07.022.CrossRefPubMed Naccarelli GV, Varker H, Lin J, Schulman KL: Increasing prevalence of atrial fibrillation and flutter in the United States. Am J Cardiol. 2009, 104: 1534-1539. 10.1016/j.amjcard.2009.07.022.CrossRefPubMed
19.
go back to reference Kirchhof P, Auricchio A, Bax J, Crijns H, Camm J, Diener HC, Goette A, Hindricks G, Hohnloser S, Kappenberger L, Kuck KH, Lip GY, Olsson B, Meinertz T, Priori S, Ravens U, Steinbeck G, Svernhage E, Tijssen J, Vincent A, Breithardt G: Outcome parameters for trials in atrial fibrillation: recommendations from a consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. Europace. 2007, 9: 1006-1023. 10.1093/europace/eum191.CrossRefPubMed Kirchhof P, Auricchio A, Bax J, Crijns H, Camm J, Diener HC, Goette A, Hindricks G, Hohnloser S, Kappenberger L, Kuck KH, Lip GY, Olsson B, Meinertz T, Priori S, Ravens U, Steinbeck G, Svernhage E, Tijssen J, Vincent A, Breithardt G: Outcome parameters for trials in atrial fibrillation: recommendations from a consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. Europace. 2007, 9: 1006-1023. 10.1093/europace/eum191.CrossRefPubMed
Metadata
Title
Trends in the use of electrical cardioversion for atrial fibrillation: influence of major trials and guidelines on clinical practice
Authors
Josep M Alegret
Xavier Viñolas
César Romero-Menor
Silvia Pons
Roger Villuendas
Naiara Calvo
Jordi Pérez-Rodon
Xavier Sabaté
and REVERCAT study investigators
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2012
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/1471-2261-12-42

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