Published in:
Open Access
01-12-2015 | Oral presentation
O066. Kynurenine pathway metabolites in cluster headache
Authors:
Martina Curto, Luana Lionetto, Matilde Capi, Andrea Negro, Lidia D'Alonzo, Ferdinando Nicoletti, Paolo Martelletti
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2015
Login to get access
Excerpt
Cluster headache is a severe, disabling disorder with pain that ranks among the most severe known to humans. It is associated with accompanying autonomic symptoms ipsilateral to the pain and a sense of restlessness or agitation. Patients with cluster headaches have few therapeutic options, and a further 10-20% develop drug-resistant attacks. The often brief duration of cluster attacks makes abortive therapy a challenge, and preventive medications are almost always provided to patients. …