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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Poster presentation

P043. Hyperechogenicity of the periaqueductal gray in chronic migraine and episodic migraine as a potential marker of progressive dysfunction: preliminary results with transcranial sonography

Authors: Elena Guaschino, Natascia Ghiotto, Cristina Tassorelli, Vito Bitetto, Giuseppe Nappi, Arrigo Moglia, Daniele Bosone, Grazia Sances

Published in: The Journal of Headache and Pain | Special Issue 1/2015

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Excerpt

It is widely accepted that the brainstem plays a role in migraine pathophysiology. The periaqueductal gray matter (PAG) is a substantial component of the descending pain modulatory network. Previous MRI studies by Welch et al demonstrated that PAG iron levels are abnormally high both in episodic and chronic migraine, suggesting the hypothesis that iron accumulation may be a marker of progressive PAG dysfunction. The increase in iron levels can be investigated with transcranial sonography (TCS) because of heavy metal-induced hyperechogenicity. …
Metadata
Title
P043. Hyperechogenicity of the periaqueductal gray in chronic migraine and episodic migraine as a potential marker of progressive dysfunction: preliminary results with transcranial sonography
Authors
Elena Guaschino
Natascia Ghiotto
Cristina Tassorelli
Vito Bitetto
Giuseppe Nappi
Arrigo Moglia
Daniele Bosone
Grazia Sances
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-16-S1-A61

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