Published in:
Open Access
01-12-2014 | Meeting abstract
EHMTI-0085. White matter microstructure abnormalities in pediatric migraine patients: in-vivo measures of brain hyperexcitability?
Authors:
R Messina, MA Rocca, B Colombo, E Pagani, A Falini, G Comi, M Filippi
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2014
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Excerpt
By exploiting diffusion characteristics of water molecules in the central nervous system, diffusion tensor (DT) magnetic resonance imaging (MRI) provides several quantities with the potential to disclose WM microstructure abnormalities. Among these, fractional anisotropy (FA) reflects axonal integrity and fiber organization, mean diffusivity (MD) measures the overall magnitude of diffusion, axial diffusivity (AD) is associated with fiber density and axon intrinsic characteristics, whereas radial diffusivity (RD) reflects the degree of myelination. …