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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2014

Open Access 01-12-2014 | Meeting abstract

EHMTI-0141. URB937 as a potential therapeutic option for migraine: evaluation in animal model of migraine

Authors: R Greco, T Bandiera, AS Mangione, F Siani, G Nappi, G Sandrini, A Guijarro, A Armirotti, D Piomelli, C Tassorelli

Published in: The Journal of Headache and Pain | Special Issue 1/2014

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Excerpt

Systemic nitroglycerin (NTG) activates cerebral nuclei of rat involved in nociceptive transmission, as well as in neuroendocrine and autonomic functions. These changes are considered relevant for migraine pain, since NTG consistently provokes spontaneous-like migraine attacks in migraineurs. Several reports have suggested the existence of relations between the endocannabinoids and migraine. URB937, a peripheral fatty acid amide hydrolase (FAAH) inhibitor, induces analgesia in animal models of pain but there is no information on its effects in migraine. …
Metadata
Title
EHMTI-0141. URB937 as a potential therapeutic option for migraine: evaluation in animal model of migraine
Authors
R Greco
T Bandiera
AS Mangione
F Siani
G Nappi
G Sandrini
A Guijarro
A Armirotti
D Piomelli
C Tassorelli
Publication date
01-12-2014
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2014
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-15-S1-F27

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