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Cancer Cell International
Published in: Cancer Cell International 1/2020

Open Access 01-12-2020 | Glioma | Review

CRNDE: an oncogenic long non-coding RNA in cancers

Authors: Ya Lu, Huanhuan Sha, Xun Sun, Yuan Zhang, Yang Wu, Junying Zhang, Hui Zhang, Jianzhong Wu, Jifeng Feng

Published in: Cancer Cell International | Issue 1/2020

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Abstract

Colorectal neoplasia differentially expressed (CRNDE) is a long non-coding RNA which has been proved upregulated in various cancers. Meanwhile, CRNDE has been demonstrated to be involved in multiple biological processes of different cancers according to previous study. Moreover, recent studies suggested CRNDE might be a potential diagnostic biomarker and prognostic predictor due to its high sensitivity and specificity in cancer tissues and plasma. In this review, we summarize the biological function of CRNDE and the relevant mechanisms in cancers to establish a molecular basis for the clinical use of CRNDE in the future.
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Metadata
Title
CRNDE: an oncogenic long non-coding RNA in cancers
Authors
Ya Lu
Huanhuan Sha
Xun Sun
Yuan Zhang
Yang Wu
Junying Zhang
Hui Zhang
Jianzhong Wu
Jifeng Feng
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Cancer Cell International / Issue 1/2020
Electronic ISSN: 1475-2867
DOI
https://doi.org/10.1186/s12935-020-01246-3

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