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BMC Gastroenterology
Published in: BMC Gastroenterology 1/2022

Open Access 01-12-2022 | Computed Tomography | Case report

Undifferentiated high-grade pleomorphic sarcoma of the colon: a rare case report and literature review

Authors: Xu Han, Linxian Zhao, Yu Mu, Guoliang Liu, Guohong Zhao, Hongyu He, Shu Wang, Jiannan Li

Published in: BMC Gastroenterology | Issue 1/2022

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Abstract

Background

Undifferentiated pleomorphic sarcoma (UPS), also known as malignant fibrous histiocytoma (MFH), hardly originates from the colorectum.

Case presentation

We reported a 65-year-old female presented with UPS in the descending colon. Computed tomography (CT) revealed an irregularly thickened descending colon. On colonoscopy examination, an ulcerative tumour was identified. The patient received radical resection of the left colon and partial enterectomy. The resected tumor was ulcerative, 10 cm × 8 cm × 5 cm in size, and infiltrated the serosa layer. Postsurgical pathology showed that the tumor was high-graded UPS in the colon with large amounts of necrotic tissues.

Conclusions

UPS in the large intestine is a rare malignant tumor with a poor prognosis and unknown pathogenesis. The main treatment for UPS is early complete resection. Postsurgery adjuvant radiotherapy or chemotherapy can be attempted.
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Metadata
Title
Undifferentiated high-grade pleomorphic sarcoma of the colon: a rare case report and literature review
Authors
Xu Han
Linxian Zhao
Yu Mu
Guoliang Liu
Guohong Zhao
Hongyu He
Shu Wang
Jiannan Li
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2022
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-022-02189-x

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