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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Oral presentation

Single-cell analysis techniques reveal a striking heterogeneity of human CD4+ T cell subsets

Authors: M Coffre, K Placek, S Maiella, E Bianchi, L Rogge

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

Distinct CD4+ T cell subsets are necessary for efficient immune responses against various pathogens. Among these, Th17 cells play a critical role in mucosal immunity. On the other hand, Th17 cells are pathogenic in several autoimmune disease models. In addition to IL-17A, Th17 cells also produce the IL-10-related cytokine IL-22. However, recent reports have suggested that human IL-22-producing CD4+ T cells may represent a distinct T helper cell subset indicating an unexpected level of heterogeneity of CD4+ T cell “lineages”. …
Metadata
Title
Single-cell analysis techniques reveal a striking heterogeneity of human CD4+ T cell subsets
Authors
M Coffre
K Placek
S Maiella
E Bianchi
L Rogge
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-O5

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
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