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Published in: American Journal of Clinical Dermatology 4/2020

01-08-2020 | Panniculitis | Review Article

Dermatologic Sequelae Associated with Radiation Therapy

Authors: Kurt A. Ashack, Victoria Kuritza, Michael J. Visconti, Laura Ashack

Published in: American Journal of Clinical Dermatology | Issue 4/2020

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Abstract

Radiation therapy is a mainstay for the treatment of primary malignancies and metastatic disease and is associated with several dermatological adverse events that are underreported in the literature. The objective of this paper was to review the literature regarding cutaneous manifestations associated with radiation therapy in order to promote awareness of the cutaneous radiation therapy-associated adverse effects. This extensive literature review was performed using the Pubmed and Embase databases. Studies were reviewed for relevance and critical evidence pertaining to cutaneous manifestations of radiation therapy. The most commonly reported cutaneous sequelae associated with radiation therapy include radiation dermatitis, non-melanoma skin cancer, radiation-associated angiosarcoma, morphea, bullous pemphigoid, lymphangioma circumscriptum, and pseudosclerodermatous panniculitis. For many of these conditions, only case reports or case series exist and there is an absence of large-scale cohort studies. Despite these limitations, this review describes the wide range of dermatological adverse events associated with radiation therapy.
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Metadata
Title
Dermatologic Sequelae Associated with Radiation Therapy
Authors
Kurt A. Ashack
Victoria Kuritza
Michael J. Visconti
Laura Ashack
Publication date
01-08-2020
Publisher
Springer International Publishing
Published in
American Journal of Clinical Dermatology / Issue 4/2020
Print ISSN: 1175-0561
Electronic ISSN: 1179-1888
DOI
https://doi.org/10.1007/s40257-020-00519-x

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