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Infection
Published in: Infection 4/2020

01-08-2020 | Human Immunodeficiency Virus | Original Paper

HIV-1 recombinant forms in immigrants regularly residing in Milan, northern Italy

Authors: Sabrina Bagaglio, Caterina Uberti-Foppa, Caterina Sagnelli, Alessia Lai, Hamid Hasson, Stefania Salpietro, Emanuela Messina, Giulia Morsica, Chiara Zaffina, Antonello Sica, Adriano Lazzarin, Silvia Angeletti, Evangelista Sagnelli, Brian Foley, Massimo Ciccozzi

Published in: Infection | Issue 4/2020

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Abstract

To assess the HIV -1subtypes distribution in HIV-1 positive migrants living in Milan we studied 77 HIV-1 patients followed at the San Raffaele Hospital of Milan. Twenty subjects were born in Europe, 43 in the Americas, 10 in Africa and 4 in Asia. Unsafe heterosexual activity prevailed in migrants born in Africa and male homosexuality in those born in European, American and Asian countries (p = 0.05). The phylogeny showed that 38/77 (49.3%) subjects carried HIV-B subtype while the remaining strains were classified as not pure HIV-1 B subtypes 13/77 (16.9%) or recombinant forms 26/77 (33.8%). Female gender more frequently showed HIV-1 non-B strains and rarely HIV-1 B subtypes (12/39, 30.8% vs. 3/38, 7.9%, p = 0.02). Transmitted drug resistance was identified in 10/77 (13%) patients predominately with B subtype. Our data underscore a large heterogeneity in HIV-1 subtypes and a large proportion of recombinant forms.
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Metadata
Title
HIV-1 recombinant forms in immigrants regularly residing in Milan, northern Italy
Authors
Sabrina Bagaglio
Caterina Uberti-Foppa
Caterina Sagnelli
Alessia Lai
Hamid Hasson
Stefania Salpietro
Emanuela Messina
Giulia Morsica
Chiara Zaffina
Antonello Sica
Adriano Lazzarin
Silvia Angeletti
Evangelista Sagnelli
Brian Foley
Massimo Ciccozzi
Publication date
01-08-2020
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 4/2020
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-020-01434-3

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