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Published in: Infection 2/2018

01-04-2018 | Case Report

Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542–1591)

Authors: Raffaella Bianucci, Otto Appenzeller, Peter Evans, Philippe Charlier, Antonio Perciaccante

Published in: Infection | Issue 2/2018

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Abstract

Purpose

St. John of the Cross (1542–1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed.

Methods

An accurate perusal of his biography allowed the symptomatology, the clinical evolution, the depth of the infection and the associated systemic manifestations displayed by Fray John to be reconstructed.

Results

St. John of the Cross developed cellulitis in the foot, which turned into a cutaneous abscess. To treat the toxaemia and inhibit further necrosis of the skin, excision of necrotic tissue and cauterization of the sores were performed to no avail. The infection burrowed through the fascial planes and reached the bones of the leg, leading to osteomyelitis.

Conclusions

In the absence of antibiotic treatments and proper antiseptic procedures, the soft-tissue infection spread deeper to the bones. It is not unconceivable that the surgery might have further promoted the spread of the bacteria giving rise to the secondary sepsis that led to St. John’s premature death.
Literature
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go back to reference Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SV, Montoya JG, Wade JC. Infectious Disease Society of America. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59:e10–52.CrossRefPubMed Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SV, Montoya JG, Wade JC. Infectious Disease Society of America. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59:e10–52.CrossRefPubMed
Metadata
Title
Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542–1591)
Authors
Raffaella Bianucci
Otto Appenzeller
Peter Evans
Philippe Charlier
Antonio Perciaccante
Publication date
01-04-2018
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 2/2018
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-017-1089-x

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