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Infection
Published in: Infection 5/2017

01-10-2017 | Brief Report

Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay

Authors: Yu Pang, Jie Lu, Biyi Su, Huiwen Zheng, Yanlin Zhao

Published in: Infection | Issue 5/2017

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Abstract

Out of 12 nontuberculous mycobacteria (NTM) species, 5 were identified as Mycobacterium tuberculosis (MTB) by GeneXpert at a bacterial load of 106. Notably, two species, including M. abscessus and M. smegmatis, were flagged as RIF-resistant MTB due to the high C(t) value of Probe E. In conclusion, our data have demonstrated that the misdiagnosis of MTB by GeneXpert assay is observed in five NTM species at a high bacterial load.
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Metadata
Title
Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay
Authors
Yu Pang
Jie Lu
Biyi Su
Huiwen Zheng
Yanlin Zhao
Publication date
01-10-2017
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 5/2017
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-017-1044-x

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