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Infection
Published in: Infection 4/2016

01-08-2016 | Case Report

The rationale for third trimester testing of vertical HIV transmission in neonates with CMV infection

Authors: Vinzenz Boos, Cornelia Feiterna-Sperling, Akosua Sarpong, Lars Garten, Malte Cremer, Katharina von Weizsäcker, Christoph Bührer, Christof Dame

Published in: Infection | Issue 4/2016

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Abstract

We report on a late-preterm neonate with severe congenital cytomegalovirus (CMV) infection, refractory to antiviral therapy with ganciclovir. Subsequent immune diagnostics led to the finding of HIV infection at day 69, even though the mother tested negative for HIV in early pregnancy. Thus, in congenital CMV infection, HIV testing should be performed to elucidate maternal HIV seroconversion during late pregnancy. Our case strongly supports third trimester screening of HIV infection acquired during pregnancy, yet recommended only for women with traditional risk factors for HIV or living in an area of high HIV prevalence.
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Metadata
Title
The rationale for third trimester testing of vertical HIV transmission in neonates with CMV infection
Authors
Vinzenz Boos
Cornelia Feiterna-Sperling
Akosua Sarpong
Lars Garten
Malte Cremer
Katharina von Weizsäcker
Christoph Bührer
Christof Dame
Publication date
01-08-2016
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 4/2016
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-016-0876-0

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