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Infection
Published in: Infection 5/2015

01-10-2015 | Brief Report

Epidemiological characteristics of bloodstream infections in patients with different degrees of liver disease

Authors: Micaela Brandolini, Marta Corbella, Annalisa De Silvestri, Carmine Tinelli, Giulia Albonico, Riccardo Albertini, Serena Ludovisi, Raffaele Bruno, Piero Marone, Lorenzo Minoli, Elena Seminari

Published in: Infection | Issue 5/2015

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Abstract

Observational retrospective study to evaluate the etiology, the outcome and the risk factors of bloodstream infections (BSIs) in patients with liver disease. One hundred and forty-eight BSIs were diagnosed (infection rate: 0.60 per 100 days of hospital stay), 62 BSIs (41.9 %) were associated with Gram-positive bacteria (infection rate: 0.25 per 100 days of hospital stay) and 80 (54.4 %) with Gram-negative bacteria (infection rate: 0.32 per 100 days of hospital stay). Admission-associated mortality was higher in patients with BSI than in those without BSI (20.6 versus 5.0 %, p < 0.001). Patients with cirrhosis had an increased risk to develop a BSI compared with patients with chronic hepatitis, specifically for Gram-positive (and Staphylococcus spp)-related BSI.
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Metadata
Title
Epidemiological characteristics of bloodstream infections in patients with different degrees of liver disease
Authors
Micaela Brandolini
Marta Corbella
Annalisa De Silvestri
Carmine Tinelli
Giulia Albonico
Riccardo Albertini
Serena Ludovisi
Raffaele Bruno
Piero Marone
Lorenzo Minoli
Elena Seminari
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 5/2015
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-015-0794-6

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