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01-02-2013 | Case Report

Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis

Authors: M. Cagliuso, V. Conti, S. Trasarti, L. Lombardi, M. Riminucci, M. Perez, O. Turriziani, F. Falasca, M. Nanni, A. Tafuri, I. Mezzaroma

Published in: Infection | Issue 1/2013

Abstract

A rare case of splenic marginal zone lymphoma (SMZL) in a human immunodeficiency virus (HIV)-1 infected patient is described. As an association between SMZL and viral infections has been reported, the presence of the hepatitis C virus and HIV-1 genomes was evaluated. Only HIV-1 DNA levels were detected in enriched splenic B lymphocytes, suggesting a HIV-1 involvement in lymphomagenesis.

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Title: Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis
Authors: M. Cagliuso
V. Conti
S. Trasarti
L. Lombardi
M. Riminucci
M. Perez
O. Turriziani
F. Falasca
M. Nanni
A. Tafuri
I. Mezzaroma
Publication date: 01-02-2013
Publisher: Springer-Verlag
Published in: Infection / Issue 1/2013
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-012-0344-4

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