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Infection
Published in: Infection 6/2012

01-12-2012 | Case Report

Dengue virus identification by transmission electron microscopy and molecular methods in fatal dengue hemorrhagic fever

Authors: D. Limonta, V. Falcón, G. Torres, V. Capó, I. Menéndez, D. Rosario, Y. Castellanos, M. Alvarez, R. Rodríguez-Roche, M. C. de la Rosa, A. Pavón, L. López, K. González, G. Guillén, J. Diaz, M. G. Guzmán

Published in: Infection | Issue 6/2012

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Abstract

Dengue virus is the most significant virus transmitted by arthropods worldwide and may cause a potentially fatal systemic disease named dengue hemorrhagic fever. In this work, dengue virus serotype 4 was detected in the tissues of one fatal dengue hemorrhagic fever case using electron immunomicroscopy and molecular methods. This is the first report of dengue virus polypeptides findings by electron immunomicroscopy in human samples. In addition, not-previously-documented virus-like particles visualized in spleen, hepatic, brain, and pulmonary tissues from a dengue case are discussed.
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Metadata
Title
Dengue virus identification by transmission electron microscopy and molecular methods in fatal dengue hemorrhagic fever
Authors
D. Limonta
V. Falcón
G. Torres
V. Capó
I. Menéndez
D. Rosario
Y. Castellanos
M. Alvarez
R. Rodríguez-Roche
M. C. de la Rosa
A. Pavón
L. López
K. González
G. Guillén
J. Diaz
M. G. Guzmán
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Infection / Issue 6/2012
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-012-0260-7

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