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Journal of Cachexia, Sarcopenia and Muscle
Published in: Journal of Cachexia, Sarcopenia and Muscle 3/2014

01-09-2014 | Review

Osteosarcopenic obesity: the role of bone, muscle, and fat on health

Authors: Michael J. Ormsbee, Carla M. Prado, Jasminka Z. Ilich, Sarah Purcell, Mario Siervo, Abbey Folsom, Lynn Panton

Published in: Journal of Cachexia, Sarcopenia and Muscle | Issue 3/2014

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Abstract

Osteopenia/osteoporosis, sarcopenia, and obesity are commonly observed in the process of aging, and recent evidence suggests a potential interconnection of these syndromes with common pathophysiology. The term osteosarcopenic obesity has been coined to describe the concurrent appearance of obesity in individuals with low bone and muscle mass. Although our understanding of osteosarcopenic obesity’s etiology, prevalence, and consequences is extremely limited, it is reasonable to infer its negative impact in a population that is aging in an obesogenic environment. It is likely that these individuals will present with poorer clinical outcomes caused by the cascade of metabolic abnormalities associated with these changes in body composition. Clinical outcomes include but are not limited to increased risk of fractures, impaired functional status (including activities of daily living), physical disability, insulin resistance, increased risk of infections, increased length of hospital stay, and reduced survival. These health outcomes are likely to be worse when compared to individuals with obesity, sarcopenia, or osteopenia/osteoporosis alone. Interventions that utilize resistance training exercise in conjunction with increased protein intake appear to be promising in their ability to counteract osteosarcopenic obesity.
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Metadata
Title
Osteosarcopenic obesity: the role of bone, muscle, and fat on health
Authors
Michael J. Ormsbee
Carla M. Prado
Jasminka Z. Ilich
Sarah Purcell
Mario Siervo
Abbey Folsom
Lynn Panton
Publication date
01-09-2014
Publisher
Springer Berlin Heidelberg
Published in
Journal of Cachexia, Sarcopenia and Muscle / Issue 3/2014
Print ISSN: 2190-5991
Electronic ISSN: 2190-6009
DOI
https://doi.org/10.1007/s13539-014-0146-x

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