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Published in: Diabetology International 3/2019

01-07-2019 | Short Communication

Clinical characteristics of Japanese diabetic patients with critical limb ischemia presenting Fontaine stage IV

Authors: Mitsuyoshi Takahara, Osamu Iida, Yukihiro Fujita, Masakazu Haneda

Published in: Diabetology International | Issue 3/2019

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Abstract

The aim of the current study was to reveal the clinical characteristics of Japanese diabetic patients with critical limb ischemia (CLI) presenting ischemic unhealed ulcer/gangrene (Fontaine stage IV) in the real-world settings. The current retrospective cross-sectional study included consecutive 282 Japanese diabetic patients who underwent endovascular therapy for CLI presenting Fontaine stage IV. The prevalence of diabetes-related complications was estimated adopting multiple imputation (50 times). The patients were aged 70 ± 10 years. Median duration of diabetes was 21 (interquartile range 12–31) years. The prevalence of proliferative diabetic retinopathy, end-stage renal disease on regular dialysis, stroke, coronary artery disease, and chronic heart failure was estimated at 48% (95% confidence interval 39–56%), 52% (46–58%), 34% (28–39%), 48% (42–54%), and 35% (29–41%), respectively. The prevalence of stroke, coronary artery disease, and chronic heart failure was not significantly associated with the duration of diabetes (all p > 0.05). On the other hand, the prevalence of proliferative diabetic retinopathy and end-stage renal disease on regular dialysis was significantly positively associated with the duration of diabetes (both p < 0.05). However, these prevalences reached as high as ~ 30% even in patients with duration of diabetes < 10 years. In conclusion, the advanced stage of diabetes-related complications was prevalent in patients with CLI presenting Fontaine stage IV.
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Metadata
Title
Clinical characteristics of Japanese diabetic patients with critical limb ischemia presenting Fontaine stage IV
Authors
Mitsuyoshi Takahara
Osamu Iida
Yukihiro Fujita
Masakazu Haneda
Publication date
01-07-2019
Publisher
Springer Japan
Published in
Diabetology International / Issue 3/2019
Print ISSN: 2190-1678
Electronic ISSN: 2190-1686
DOI
https://doi.org/10.1007/s13340-018-0387-6

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