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Published in: Autoimmunity Highlights 1/2016

Open Access 01-12-2016 | Case Report

An unusual association of three autoimmune disorders: celiac disease, systemic lupus erythematosus and Hashimoto’s thyroiditis

Authors: Viera Boccuti, Antonio Perrone, Alessia D’Introno, Anna Campobasso, Moris Sangineto, Carlo Sabbà

Published in: Autoimmunity Highlights | Issue 1/2016

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Abstract

Autoimmune disorders are known to be more frequent in women and often associated each others, but it is rare to see multiple autoimmune diseases in a single patient. Recently, the concept of multiple autoimmune syndrome has been introduced to describe patients with at least three autoimmune diseases. We describe a case of a young man with a clinical history of psychiatric symptoms and celiac disease (CD) who was diagnosed to have other two autoimmune disorders: systemic lupus erythematosus (SLE) and Hashimoto’s thyroiditis. This case is unusual upon different patterns: the rare combination of the three autoimmune diseases, their appearance in a man and the atypical onset of the diseases with psychiatric symptoms likely to be related either to CD or to SLE.
Literature
1.
go back to reference Dubé C, Rostom A, Sy R et al (2005) The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 128(4 Suppl 1):S57–S67CrossRefPubMed Dubé C, Rostom A, Sy R et al (2005) The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 128(4 Suppl 1):S57–S67CrossRefPubMed
2.
go back to reference Neuhausen SL, Steele L, Ryan S et al (2008) Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives. J Autoimmun 31(2):160–165CrossRefPubMedPubMedCentral Neuhausen SL, Steele L, Ryan S et al (2008) Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives. J Autoimmun 31(2):160–165CrossRefPubMedPubMedCentral
3.
go back to reference Humbert P, Dupond JL (1988) Multiple autoimmune syndromes. Ann Med Interne (Paris) 139(3):159–168 Humbert P, Dupond JL (1988) Multiple autoimmune syndromes. Ann Med Interne (Paris) 139(3):159–168
4.
go back to reference Anaya JM, Corena R, Castiblanco J et al (2007) The kaleidoscope of autoimmunity. Multiple autoimmune syndromes and familial autoimmunity. Expert Rev Clin Immunol 3:623–635CrossRefPubMed Anaya JM, Corena R, Castiblanco J et al (2007) The kaleidoscope of autoimmunity. Multiple autoimmune syndromes and familial autoimmunity. Expert Rev Clin Immunol 3:623–635CrossRefPubMed
5.
6.
go back to reference Mohan MP, Ramesh TC (2003) Multiple autoimmune syndrome. Indian J Dermatol Venereol Leprol 69:298–299PubMed Mohan MP, Ramesh TC (2003) Multiple autoimmune syndrome. Indian J Dermatol Venereol Leprol 69:298–299PubMed
8.
go back to reference Teixeira LM, Nisihara R, Utiyama SR et al (2014) Screening of celiac disease in patients with autoimmune thyroid disease from Southern Brazil. Arq Bras Endocrinol Metabol 58(6):625–629CrossRefPubMed Teixeira LM, Nisihara R, Utiyama SR et al (2014) Screening of celiac disease in patients with autoimmune thyroid disease from Southern Brazil. Arq Bras Endocrinol Metabol 58(6):625–629CrossRefPubMed
9.
go back to reference Ventura A, Ronsoni MF, Shiozawa MB et al (2014) Prevalence and clinical features of celiac disease in patients with autoimmune thyroiditis: cross-sectional study. Sao Paulo Med J 132(6):364–371CrossRefPubMed Ventura A, Ronsoni MF, Shiozawa MB et al (2014) Prevalence and clinical features of celiac disease in patients with autoimmune thyroiditis: cross-sectional study. Sao Paulo Med J 132(6):364–371CrossRefPubMed
10.
go back to reference Lin Wen-Ya, Chang Chia-Li, Lin-Shien Fu et al (2015) Systemic lupus erythematosus and thyroid disease: a 10-year study. J Microbiol Immunol Infect 48(6):676–683CrossRefPubMed Lin Wen-Ya, Chang Chia-Li, Lin-Shien Fu et al (2015) Systemic lupus erythematosus and thyroid disease: a 10-year study. J Microbiol Immunol Infect 48(6):676–683CrossRefPubMed
11.
go back to reference Ludvigsson JF, Rubio-Tapia A, Chowdhary V et al (2012) Increased risk of systemic lupus erythematosus in 29,000 patients with biopsy-verified celiac disease. J Rheumatol 39(10):1964–1970CrossRefPubMedPubMedCentral Ludvigsson JF, Rubio-Tapia A, Chowdhary V et al (2012) Increased risk of systemic lupus erythematosus in 29,000 patients with biopsy-verified celiac disease. J Rheumatol 39(10):1964–1970CrossRefPubMedPubMedCentral
12.
go back to reference Crişcov GI, Stana AB, Ioniue IK et al (2015) Coexistence of celiac disease and systemic lupus erythematosus in a 6-year-old girl-case report. Rev Med Chir Soc Med Nat Iasi 119(1):87–91PubMed Crişcov GI, Stana AB, Ioniue IK et al (2015) Coexistence of celiac disease and systemic lupus erythematosus in a 6-year-old girl-case report. Rev Med Chir Soc Med Nat Iasi 119(1):87–91PubMed
13.
go back to reference Freeman HJ (2008) Adult celiac disease followed by onset of systemic lupus erythematosus. J Clin Gastroenterol 42:252–255PubMed Freeman HJ (2008) Adult celiac disease followed by onset of systemic lupus erythematosus. J Clin Gastroenterol 42:252–255PubMed
14.
go back to reference Latif S, Jamal A, Memon I et al (2010) Multiple autoimmune syndrome: Hashimoto’s thyroiditis, coeliac disease and systemic lupus erythematosus (SLE). J Pak Med Assoc 60(10):863–865PubMed Latif S, Jamal A, Memon I et al (2010) Multiple autoimmune syndrome: Hashimoto’s thyroiditis, coeliac disease and systemic lupus erythematosus (SLE). J Pak Med Assoc 60(10):863–865PubMed
15.
16.
go back to reference Pego-Reigosa JM, Isenberg DA (2008) Psychosis due to systemic lupus erythematosus: characteristics and long-term outcome of this rare manifestation of the disease. Rheumatology 47:1498–1502CrossRefPubMed Pego-Reigosa JM, Isenberg DA (2008) Psychosis due to systemic lupus erythematosus: characteristics and long-term outcome of this rare manifestation of the disease. Rheumatology 47:1498–1502CrossRefPubMed
17.
go back to reference Jackson JR, Eaton WW, Cascella NG et al (2012) Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity. Psychiatr Q 83(1):91–102CrossRefPubMedPubMedCentral Jackson JR, Eaton WW, Cascella NG et al (2012) Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity. Psychiatr Q 83(1):91–102CrossRefPubMedPubMedCentral
Metadata
Title
An unusual association of three autoimmune disorders: celiac disease, systemic lupus erythematosus and Hashimoto’s thyroiditis
Authors
Viera Boccuti
Antonio Perrone
Alessia D’Introno
Anna Campobasso
Moris Sangineto
Carlo Sabbà
Publication date
01-12-2016
Publisher
Springer International Publishing
Published in
Autoimmunity Highlights / Issue 1/2016
Print ISSN: 2038-0305
Electronic ISSN: 2038-3274
DOI
https://doi.org/10.1007/s13317-016-0079-9

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