Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Neurotherapeutics
Published in: Neurotherapeutics 1/2019

01-01-2019 | Review

Tractography for Surgical Neuro-Oncology Planning: Towards a Gold Standard

Authors: Sandip S. Panesar, Kumar Abhinav, Fang-Cheng Yeh, Timothée Jacquesson, Malie Collins, Juan Fernandez-Miranda

Published in: Neurotherapeutics | Issue 1/2019

Login to get access

Abstract

Magnetic resonance imaging tractography permits in vivo visualization of white matter structures. Aside from its academic value, tractography has been proven particularly useful to neurosurgeons for preoperative planning. Preoperative tractography permits both qualitative and quantitative analyses of tumor effects upon surrounding white matter, allowing the surgeon to specifically tailor their operative approach. Despite its benefits, there is controversy pertaining to methodology, implementation, and interpretation of results in this context. High-definition fiber tractography (HDFT) is one of several non-tensor tractography approaches permitting visualization of crossing white matter trajectories at high resolutions, dispensing with the well-known shortcomings of diffusion tensor imaging (DTI) tractography. In this article, we provide an overview of the advantages of HDFT in a neurosurgical context, derived from our considerable experience implementing the technique for academic and clinical purposes. We highlight nuances of qualitative and quantitative approaches to using HDFT for brain tumor surgery planning, and integration of tractography with complementary operative adjuncts, and consider areas requiring further research.
Literature
1.
Schmahmann JD, Pandya DN. Cerebral White Matter—Historical Evolution of Facts and Notions Concerning the Organization of the Fiber Pathways of the Brain. J Hist Neurosci. 2007;16(3):237–67.CrossRefPubMed
2.
de Schotten MT, Dell’Acqua F, Valabregue R, Catani M. Monkey to human comparative anatomy of the frontal lobe association tracts. Cortex. 2012;48(1):82–96.CrossRef
3.
Forkel SJ, de Schotten MT, Kawadler JM, Dell’Acqua F, Danek A, Catani M. The anatomy of fronto-occipital connections from early blunt dissections to contemporary tractography. Cortex. 2014;56:73–84.CrossRefPubMed
4.
Celtikci P, Fernandes-Cabral DT, Yeh F-C, Panesar SS, Fernandez-Miranda JC. Generalized q-sampling imaging fiber tractography reveals displacement and infiltration of fiber tracts in low-grade gliomas. Neuroradiology. 2018;60(3):267–80.CrossRefPubMed
5.
Abhinav K, Yeh F-C, Mansouri A, Zadeh G, Fernandez-Miranda JC. High-definition fiber tractography for the evaluation of perilesional white matter tracts in high-grade glioma surgery. Neuro-Oncol. 2015;17(9):1199–209.PubMedPubMedCentral
6.
Abhinav K, Pathak S, Richardson RM, Engh J, Gardner P, Yeh F-C, et al. Application of High-Definition Fiber Tractography in the Management of Supratentorial Cavernous Malformations: A Combined Qualitative and Quantitative Approach. Neurosurgery. 2014;74(6):668–81.CrossRefPubMed
7.
8.
Farquharson S, Tournier J-D, Calamante F, Fabinyi G, Schneider-Kolsky M, Jackson GD, et al. White matter fiber tractography: why we need to move beyond DTI. J Neurosurg. 2013;118(6):1367–77.CrossRefPubMed
9.
Fernandez-Miranda JC, Pathak S, Engh J, Jarbo K, Verstynen T, Yeh F-C, et al. High-definition fiber tractography of the human brain: neuroanatomical validation and neurosurgical applications. Neurosurgery. 2012;71(2):430–53.CrossRefPubMed
10.
Fernandez-Miranda JC, Engh JA, Pathak SK, Madhok R, Boada FE, Schneider W, et al. High-definition fiber tracking guidance for intraparenchymal endoscopic port surgery. J Neurosurg. 2009;113(5):990–9.CrossRefPubMed
11.
Fernández-Miranda JC, Wang Y, Pathak S, Stefaneau L, Verstynen T, Yeh F-C. Asymmetry, connectivity, and segmentation of the arcuate fascicle in the human brain. Brain Struct Funct. 2015;220(3):1665–80.CrossRefPubMed
12.
Wang X, Pathak S, Stefaneanu L, Yeh F-C, Li S, Fernandez-Miranda JC. Subcomponents and connectivity of the superior longitudinal fasciculus in the human brain. Brain Struct Funct. 2016;221(4):2075–92.CrossRefPubMed
13.
Panesar SS, Yeh FC, Deibert CP, Fernandes-Cabral D, Rowthu V, Celtikci P, Celtikci E, Hula WD, Pathak S, Fernández-Miranda JC. A diffusion spectrum imaging-based tractographic study into the anatomical subdivision and cortical connectivity of the ventral external capsule: uncinate and inferior fronto-occipital fascicles. Neuroradiology. 2017;59(10):971–87.
14.
Panesar SS, Yeh F-C, Deibert CP, Fernandes-Cabral D, Rowthu V, Celtikci P, et al. A diffusion spectrum imaging-based tractographic study into the anatomical subdivision and cortical connectivity of the ventral external capsule: uncinate and inferior fronto-occipital fascicles. Neuroradiology. 2017;59(10):971–87.CrossRefPubMed
15.
Wang Y, Fernández-Miranda JC, Verstynen T, Pathak S, Schneider W, Yeh F-C. Rethinking the role of the middle longitudinal fascicle in language and auditory pathways. Cereb Cortex N Y N 1991. 2013 23(10):2347–56.
16.
Yoshino M, Abhinav K, Yeh F-C, Panesar S, Fernandes D, Pathak S, et al. Visualization of Cranial Nerves Using High-Definition Fiber Tractography. Neurosurgery. 2016;79(1):146–65.CrossRefPubMed
17.
Abhinav K, Yeh F-C, Pathak S, Suski V, Lacomis D, Friedlander RM, et al. Advanced diffusion MRI fiber tracking in neurosurgical and neurodegenerative disorders and neuroanatomical studies: A review. Biochim Biophys Acta BBA - Mol Basis Dis. 2014;1842(11):2286–97.CrossRef
18.
Yeh F-C, Panesar S, Fernandes D, Meola A, Yoshino M, Fernandez-Miranda JC, et al. Population-averaged atlas of the macroscale human structural connectome and its network topology. NeuroImage. 2018;178:57–68.CrossRefPubMed
19.
Stejskal EO, Tanner JE. Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient. J Chem Phys. 1965;42(1):288–92.CrossRef
20.
Jbabdi S, Behrens TEJ, Smith SM. Crossing fibres in tract-based spatial statistics. NeuroImage. 2010;49(1):249–56.CrossRefPubMed
21.
Tuch DS, Reese TG, Wiegell MR, Makris N, Belliveau JW, Wedeen VJ. High angular resolution diffusion imaging reveals intravoxel white matter fiber heterogeneity. Magn Reson Med. 48(4):577–82.
22.
Chung H-W, Chou M-C, Chen C-Y. Principles and limitations of computational algorithms in clinical diffusion tensor MR tractography. AJNR Am J Neuroradiol. 2011;32(1):3–13.CrossRefPubMed
23.
Alexander AL, Hasan KM, Lazar M, Tsuruda JS, Parker DL. Analysis of partial volume effects in diffusion-tensor MRI. Magn Reson Med. 2001;45(5):770–80.CrossRefPubMed
24.
Pasternak O, Sochen N, Gur Y, Intrator N, Assaf Y. Free water elimination and mapping from diffusion MRI. Magn Reson Med. 2009;62(3):717–30.CrossRefPubMed
25.
Liu C, Bammer R, Acar B, Moseley ME. Characterizing non-Gaussian diffusion by using generalized diffusion tensors. Magn Reson Med. 2004;51(5):924–37.CrossRefPubMed
26.
Alexander DC, Barker GJ, Arridge SR. Detection and modeling of non-Gaussian apparent diffusion coefficient profiles in human brain data. Magn Reson Med. 2002;48(2):331–40.CrossRefPubMed
27.
Le Bihan D, Poupon C, Amadon A, Lethimonnier F. Artifacts and pitfalls in diffusion MRI. J Magn Reson Imaging JMRI. 2006;24(3):478–88.CrossRefPubMed
28.
Jellison BJ, Field AS, Medow J, Lazar M, Salamat MS, Alexander AL. Diffusion Tensor Imaging of Cerebral White Matter: A Pictorial Review of Physics, Fiber Tract Anatomy, and Tumor Imaging Patterns. Am J Neuroradiol. 2004;25(3):356–69.PubMed
29.
Yeh F-C, Wedeen VJ, Tseng W-YI. Generalized q-sampling imaging. IEEE Trans Med Imaging. 2010;29(9):1626–35.CrossRefPubMed
30.
Wedeen VJ, Wang RP, Schmahmann JD, Benner T, Tseng W-YI, Dai G, et al. Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers. Neuroimage. 2008;41(4):1267–77.CrossRefPubMed
31.
Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med. 1996;36(6):893–906.CrossRefPubMed
32.
Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di Chiro G. Diffusion tensor MR imaging of the human brain. Radiology. 1996;201(3):637–48.CrossRefPubMed
33.
Yeh F-C, Verstynen TD, Wang Y, Fernández-Miranda JC, Tseng W-YI. Deterministic diffusion fiber tracking improved by quantitative anisotropy. PloS One. 2013;8(11):e80713.CrossRefPubMedPubMedCentral
34.
Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, et al. Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J Neurosurg. 2002;97(3):568–75.CrossRefPubMed
35.
Wei CW, Guo G, Mikulis DJ. Tumor effects on cerebral white matter as characterized by diffusion tensor tractography. Can J Neurol Sci J Can Sci Neurol. 2007;34(1):62–8.CrossRef
36.
Faraji AH, Abhinav K, Jarbo K, Yeh F-C, Shin SS, Pathak S, et al. Longitudinal evaluation of corticospinal tract in patients with resected brainstem cavernous malformations using high-definition fiber tractography and diffusion connectometry analysis: preliminary experience. J Neurosurg. 2015;123(5):1133–44.CrossRefPubMed
37.
Price SJ, Burnet NG, Donovan T, Green HAL, Peña A, Antoun NM, et al. Diffusion Tensor Imaging of Brain Tumours at 3T: A Potential Tool for Assessing White Matter Tract Invasion? Clin Radiol. 2003;58(6):455–62.CrossRefPubMed
38.
Vos SB, Jones DK, Jeurissen B, Viergever MA, Leemans A. The influence of complex white matter architecture on the mean diffusivity in diffusion tensor MRI of the human brain. NeuroImage. 2012;59(3):2208–16.CrossRefPubMed
39.
Zhang H, Wang Y, Lu T, Qiu B, Tang Y, Ou S, et al. Differences between generalized q-sampling imaging and diffusion tensor imaging in the preoperative visualization of the nerve fiber tracts within peritumoral edema in brain. Neurosurgery. 2013;73(6):1044–53; discussion 1053.CrossRefPubMed
40.
Kuhnt D, Bauer MHA, Sommer J, Merhof D, Nimsky C. Optic Radiation Fiber Tractography in Glioma Patients Based on High Angular Resolution Diffusion Imaging with Compressed Sensing Compared with Diffusion Tensor Imaging—Initial Experience. PLOS ONE. 2013;8(7):e70973.CrossRefPubMedPubMedCentral
41.
Kuhnt D, Bauer MHA, Egger J, Richter M, Kapur T, Sommer J, et al. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience. Neurosurgery. 2013;72 Suppl 1:165–75.PubMedPubMedCentral
42.
Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Taillandier L, et al. Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neurosurg. 2003;98(4):764–78.CrossRefPubMed
43.
Jacquesson T, Frindel C, Kocevar G, Berhouma M, Jouanneau E, Attyé A, Cotton F. Overcoming challenges of cranial nerve tractography: a targeted review. Neurosurgery. Accessed 12 Jul 2018.
44.
Raval A, Schulder M, Kingsley P. NI-66Color coded maps of white matter tracts: NO need for tractography. Neuro-Oncol. 2014;16(suppl_5):v153–v153.CrossRefPubMedCentral
45.
Yu CS, Li KC, Xuan Y, Ji XM, Qin W. Diffusion tensor tractography in patients with cerebral tumors: A helpful technique for neurosurgical planning and postoperative assessment. Eur J Radiol. 2005;56(2):197–204.CrossRefPubMed
46.
Price SJ, Peña A, Burnet NG, Jena R, Green HAL, Carpenter TA, et al. Tissue signature characterisation of diffusion tensor abnormalities in cerebral gliomas. Eur Radiol. 2004;14(10):1909–17.CrossRefPubMed
47.
Goebell E, Paustenbach S, Vaeterlein O, Ding X-Q, Heese O, Fiehler J, et al. Low-grade and anaplastic gliomas: differences in architecture evaluated with diffusion-tensor MR imaging. Radiology. 2006;239(1):217–22.CrossRefPubMed
48.
Talos I-F, Zou KH, Kikinis R, Jolesz FA. Volumetric assessment of tumor infiltration of adjacent white matter based on anatomic MRI and diffusion tensor tractography. Acad Radiol. 2007;14(4):431–6.CrossRefPubMedPubMedCentral
49.
Delgado AF, Nilsson M, Latini F, Mårtensson J, Zetterling M, Berntsson SG, et al. Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III: A Prospective Cohort Study. Radiol Res Pract. 2016;2016:7671854.PubMedPubMedCentral
50.
Lazar M, Alexander AL, Thottakara PJ, Badie B, Field AS. White matter reorganization after surgical resection of brain tumors and vascular malformations. AJNR Am J Neuroradiol. 2006;27(6):1258–71.PubMed
51.
Louis DN, Perry A, Reifenberger G, Deimling A von, Figarella-Branger D, Cavenee WK, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol (Berl). 2016;131(6):803–20.
52.
53.
Mori S, Frederiksen K, Zijl PCM van, Stieltjes B, Kraut MA, Solaiyappan M, et al. Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging. Ann Neurol. 2002;51(3):377–80.
54.
Bihan DL. Looking into the functional architecture of the brain with diffusion MRI. Nat Rev Neurosci. 2003;4(6):469–80.CrossRefPubMed
55.
Castellano A, Bello L, Michelozzi C, Gallucci M, Fava E, Iadanza A, et al. Role of diffusion tensor magnetic resonance tractography in predicting the extent of resection in glioma surgery. Neuro-Oncol. 2012;14(2):192–202.CrossRefPubMed
56.
Moffat BA, Chenevert TL, Lawrence TS, Meyer CR, Johnson TD, Dong Q, et al. Functional diffusion map: A noninvasive MRI biomarker for early stratification of clinical brain tumor response. Proc Natl Acad Sci. 2005;102(15):5524–9.CrossRefPubMed
57.
Beppu T, Inoue T, Shibata Y, Yamada N, Kurose A, Ogasawara K, et al. Fractional anisotropy value by diffusion tensor magnetic resonance imaging as a predictor of cell density and proliferation activity of glioblastomas. Surg Neurol. 2005;63(1):56–61.CrossRefPubMed
58.
Hamstra DA, Galbán CJ, Meyer CR, Johnson TD, Sundgren PC, Tsien C, et al. Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival. J Clin Oncol Off J Am Soc Clin Oncol. 2008;26(20):3387–94.CrossRef
59.
Mardor Y, Roth Y, Ochershvilli A, Spiegelmann R, Tichler T, Daniels D, et al. Pretreatment prediction of brain tumors’ response to radiation therapy using high b-value diffusion-weighted MRI. Neoplasia N Y N. 2004;6(2):136–42.CrossRef
60.
Chen X, Weigel D, Ganslandt O, Buchfelder M, Nimsky C. Prediction of visual field deficits by diffusion tensor imaging in temporal lobe epilepsy surgery. NeuroImage. 2009;45(2):286–97.CrossRefPubMed
61.
Holodny AI, Ollenschleger MD, Liu W-C, Schulder M, Kalnin AJ. Identification of the Corticospinal Tracts Achieved Using Blood-oxygen-level–dependent and Diffusion Functional MR Imaging in Patients with Brain Tumors. Am J Neuroradiol. 2001;22(1):83–8.PubMed
62.
Bartolomei F, Bosma I, Klein M, Baayen JC, Reijneveld JC, Postma TJ, et al. How do brain tumors alter functional connectivity? A magnetoencephalography study. Ann Neurol. 2006;59(1):128–38.CrossRefPubMed
63.
Schonberg T, Pianka P, Hendler T, Pasternak O, Assaf Y. Characterization of displaced white matter by brain tumors using combined DTI and fMRI. NeuroImage. 2006;30(4):1100–11.CrossRefPubMed
64.
Schiffbauer H, Ferrari P, Rowley HA, Berger MS, Roberts TPL. Functional Activity within Brain Tumors: A Magnetic Source Imaging Study. Neurosurgery. 2001;49(6):1313–21.CrossRefPubMed
65.
Gaetz W, Scantlebury N, Widjaja E, Rutka J, Bouffet E, Rockel C, et al. Mapping of the cortical spinal tracts using magnetoencephalography and diffusion tensor tractography in pediatric brain tumor patients. Childs Nerv Syst. 2010;26(11):1639–45.CrossRefPubMed
66.
Kamada K, Todo T, Masutani Y, Aoki S, Ino K, et al. Visualization of the frontotemporal language fibers by tractography combined with functional magnetic resonance imaging and magnetoencephalography. J Neurosurg. 2007;106(1):90–8.CrossRefPubMed
67.
Berman JI, Berger MS, Chung S, Nagarajan SS, Henry RG. Accuracy of diffusion tensor magnetic resonance imaging tractography assessed using intraoperative subcortical stimulation mapping and magnetic source imaging. J Neurosurg. 2007;107(3):488–94.CrossRefPubMed
68.
Bookheimer S. Pre-Surgical Language Mapping with Functional Magnetic Resonance Imaging. Neuropsychol Rev. 2007;17(2):145–55.CrossRefPubMed
69.
Duffau H, Gatignol P, Mandonnet E, Capelle L, Taillandier L. Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere. J Neurosurg. 2008;109(3):461–71.CrossRefPubMed
70.
Sanai N, Mirzadeh Z, Berger MS. Functional Outcome after Language Mapping for Glioma Resection. N Engl J Med. 2008;358(1):18–27.CrossRefPubMed
71.
Szelényi A, Bello L, Duffau H, Fava E, Feigl GC, Galanda M, et al. Intraoperative electrical stimulation in awake craniotomy: methodological aspects of current practice. Neurosurg Focus. 2010;28(2):E7.CrossRefPubMed
72.
Borchers S, Himmelbach M, Logothetis N, Karnath H-O. Direct electrical stimulation of human cortex—the gold standard for mapping brain functions? Nat Rev Neurosci. 2012;13(1):63.CrossRef
73.
Mandonnet E, Winkler PA, Duffau H. Direct electrical stimulation as an input gate into brain functional networks: principles, advantages and limitations. Acta Neurochir (Wien). 2010;152(2):185–93.CrossRefPubMed
74.
Leclercq D, Duffau H, Delmaire C, Capelle L, Gatignol P, Ducros M, et al. Comparison of diffusion tensor imaging tractography of language tracts and intraoperative subcortical stimulations. J Neurosurg. 2009;112(3):503–11.CrossRef
75.
Okada T, Mikuni N, Miki Y, Kikuta K, Urayama S, Hanakawa T, et al. Corticospinal Tract Localization: Integration of Diffusion-Tensor Tractography at 3-T MR Imaging with Intraoperative White Matter Stimulation Mapping—Preliminary Results. Radiology. 2006;240(3):849–57.CrossRefPubMed
76.
Bello L, Gambini A, Castellano A, Carrabba G, Acerbi F, Fava E, et al. Motor and language DTI Fiber Tracking combined with intraoperative subcortical mapping for surgical removal of gliomas. NeuroImage. 2008;39(1):369–82.CrossRefPubMed
77.
Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, Sorensen AG, et al. Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery. Neurosurgery. 2005;56(1):130–8.CrossRefPubMed
78.
Nimsky C, Ganslandt O, Merhof D, Sorensen AG, Fahlbusch R. Intraoperative visualization of the pyramidal tract by diffusion-tensor-imaging-based fiber tracking. Neuroimage. 2006;30(4):1219–29.CrossRefPubMed
79.
Sherbondy AJ, Dougherty RF, Napel S, Wandell BA. Identifying the human optic radiation using diffusion imaging and fiber tractography. J Vis 2008;8(10):12–12.CrossRefPubMedPubMedCentral
80.
Thudium MO, Campos AR, Urbach H, Clusmann H. The Basal Temporal Approach for Mesial Temporal Surgery: Sparing the Meyer Loop With Navigated Diffusion Tensor Tractography. Oper Neurosurg. 2010;67(suppl_2):ons385–90.CrossRef
81.
Nimsky C, Ganslandt O, Cerny S, Hastreiter P, Greiner G, Fahlbusch R. Quantification of, Visualization of, and Compensation for Brain Shift Using Intraoperative Magnetic Resonance Imaging. Neurosurgery. 2000;47(5):1070–80.CrossRefPubMed
82.
Kuhnt D, Bauer MH, Nimsky C. Brain shift compensation and neurosurgical image fusion using intraoperative MRI: current status and future challenges. Critical Reviews™ in Biomedical Engineering. 2012;40(3).
83.
Chen DQ, Quan J, Guha A, Tymianski M, Mikulis D, Hodaie M. Three-Dimensional In Vivo Modeling of Vestibular Schwannomas and Surrounding Cranial Nerves With Diffusion Imaging Tractography. Neurosurgery. 2011;68(4):1077–83.CrossRefPubMed
84.
Hodaie M, Quan J, Chen DQ. In Vivo Visualization of Cranial Nerve Pathways in Humans Using Diffusion-Based Tractography. Neurosurgery. 2010;66(4):788–96.CrossRefPubMed
85.
Mikami T, Minamida Y, Yamaki T, Koyanagi I, Nonaka T, Houkin K. Cranial nerve assessment in posterior fossa tumors with fast imaging employing steady-state acquisition (FIESTA). Neurosurg Rev. 2005;28(4):261–6.CrossRefPubMed
86.
Okumura Y, Suzuki M, Takemura A, Tsujii H, Kawahara K, Matsuura Y, et al. [Visualization of the lower cranial nerves by 3D-FIESTA]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2005;61(2):291–7.CrossRefPubMed
87.
Taoka T, Hirabayashi H, Nakagawa H, Sakamoto M, Myochin K, Hirohashi S, et al. Displacement of the facial nerve course by vestibular schwannoma: preoperative visualization using diffusion tensor tractography. J Magn Reson Imaging Off J Int Soc Magn Reson Med. 2006;24(5):1005–10.
88.
Cauley KA, Filippi CG. Diffusion-tensor imaging of small nerve bundles: cranial nerves, peripheral nerves, distal spinal cord, and lumbar nerve roots—clinical applications. Am J Roentgenol. 2013;201(2):W326–35.CrossRef
89.
Wei P-H, Qi Z-G, Chen G, Hu P, Li M-C, Liang J-T, et al. Identification of cranial nerves near large vestibular schwannomas using superselective diffusion tensor tractography: experience with 23 cases. Acta Neurochir (Wien). 2015;157(7):1239–49.CrossRefPubMed
90.
Kakizawa Y, Seguchi T, Kodama K, Ogiwara T, Sasaki T, Goto T, et al. Anatomical study of the trigeminal and facial cranial nerves with the aid of 3.0-tesla magnetic resonance imaging. 2008
91.
Hodaie M, Chen DQ, Quan J, Laperriere N. Tractography delineates microstructural changes in the trigeminal nerve after focal radiosurgery for trigeminal neuralgia. PloS One. 2012;7(3):e32745.CrossRefPubMedPubMedCentral
92.
Herweh C, Kress B, Rasche D, Tronnier V, Tröger J, Sartor K, et al. Loss of anisotropy in trigeminal neuralgia revealed by diffusion tensor imaging. Neurology. 2007;68(10):776–8.CrossRefPubMed
93.
Leal PRL, Roch JA, Hermier M, Souza MAN, Cristino-Filho G, Sindou M. Structural abnormalities of the trigeminal root revealed by diffusion tensor imaging in patients with trigeminal neuralgia caused by neurovascular compression: a prospective, double-blind, controlled study. PAIN®. 2011;152(10):2357–64.CrossRef
94.
Lutz J, Linn J, Mehrkens JH, Thon N, Stahl R, Seelos K, et al. Trigeminal neuralgia due to neurovascular compression: high-spatial-resolution diffusion-tensor imaging reveals microstructural neural changes. Radiology. 2011;258(2):524–30.CrossRefPubMed
95.
Fujiwara S, Sasaki M, Wada T, Kudo K, Hirooka R, Ishigaki D, et al. High-resolution Diffusion Tensor Imaging for the Detection of Diffusion Abnormalities in the Trigeminal Nerves of Patients with Trigeminal Neuralgia Caused by Neurovascular Compression. J Neuroimaging. 2011;21(2):e102–8.CrossRefPubMed
96.
Lober RM, Guzman R, Cheshier SH, Fredrick DR, Edwards MS, Yeom KW. Application of diffusion tensor tractography in pediatric optic pathway glioma. J Neurosurg Pediatr. 2012;10(4):273–80.CrossRefPubMed
97.
Anik I, Anik Y, Koc K, Ceylan S, Genc H, Altintas O, et al. Evaluation of early visual recovery in pituitary macroadenomas after endoscopic endonasal transphenoidal surgery: Quantitative assessment with diffusion tensor imaging (DTI). Acta Neurochir (Wien). 2011;153(4):831–42.CrossRefPubMed
98.
Jacquesson T, Frindel C, Cotton F. Diffusion Tensor Imaging Tractography Detecting Isolated Oculomotor Nerve Damage After Traumatic Brain Injury. World Neurosurg. 2017;100:707.e5–707.e7.CrossRef
99.
Duffau H. Diffusion Tensor Imaging Is a Research and Educational Tool, but Not Yet a Clinical Tool. World Neurosurg. 2014;82(1):e43–5.CrossRefPubMed
100.
Ciccarelli O, Catani M, Johansen-Berg H, Clark C, Thompson A. Diffusion-based tractography in neurological disorders: concepts, applications, and future developments. Lancet Neurol. 2008;7(8):715–27.CrossRefPubMed
Metadata
Title
Tractography for Surgical Neuro-Oncology Planning: Towards a Gold Standard
Authors
Sandip S. Panesar
Kumar Abhinav
Fang-Cheng Yeh
Timothée Jacquesson
Malie Collins
Juan Fernandez-Miranda
Publication date
01-01-2019
Publisher
Springer International Publishing
Published in
Neurotherapeutics / Issue 1/2019
Print ISSN: 1933-7213
Electronic ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-018-00697-x

Other articles of this Issue 1/2019

Neurotherapeutics 1/2019 Go to the issue

Review

Gene Therapy for Neurodegenerative Diseases

Review

Stereoelectroencephalography Versus Subdural Electrodes for Localization of the Epileptogenic Zone: What Is the Evidence?

Correction

Correction to: The Therapy of Congenital Myasthenic Syndromes

Review

Invasive Neuromodulation for the Treatment of Pediatric Epilepsy

Review

Automatic Removal of False Connections in Diffusion MRI Tractography Using Topology-Informed Pruning (TIP)

Review

Directional Deep Brain Stimulation