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Neurotherapeutics
Published in: Neurotherapeutics 1/2019

01-01-2019 | Review

Invasive Neuromodulation for the Treatment of Pediatric Epilepsy

Authors: Laureen D. Hachem, Han Yan, George M. Ibrahim

Published in: Neurotherapeutics | Issue 1/2019

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Abstract

Neuromodulatory strategies are increasingly adopted for the treatment of intractable epilepsy in children. These encompass a wide range of treatments aimed at externally stimulating neural circuitry in order to decrease seizure frequency. In the current review, the authors discuss the evidence for invasive neuromodulation, namely vagus nerve and deep brain stimulation in affected children. Putative mechanisms of action and biomarkers of treatment success are explored and evidence of the efficacy of invasive neuromodulation is highlighted.
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Metadata
Title
Invasive Neuromodulation for the Treatment of Pediatric Epilepsy
Authors
Laureen D. Hachem
Han Yan
George M. Ibrahim
Publication date
01-01-2019
Publisher
Springer International Publishing
Published in
Neurotherapeutics / Issue 1/2019
Print ISSN: 1933-7213
Electronic ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-018-00685-1

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