Skip to main content
Top
Published in: Updates in Surgery 3/2019

01-09-2019 | Original Article

Early ileostomy reversal after minimally invasive surgery and ERAS program for mid and low rectal cancer

Authors: Corrado Pedrazzani, Federica Secci, Eduardo Fernandes, Ivans Jelovskijs, Giulia Turri, Cristian Conti, Andrea Ruzzenente, Alfredo Guglielmi

Published in: Updates in Surgery | Issue 3/2019

Login to get access

Abstract

Diverting loop ileostomy following low anterior resection (LAR) is known to decrease quality of life and prolongs the return back to patients’ baseline activity. The aim of this retrospective study was to explore feasibility and safety of an early ileostomy reversal strategy in a cohort of patients undergoing minimally invasive LAR within an enhanced recovery after surgery (ERAS) program. Prospectively collected data from 15 patients who underwent minimally invasive LAR and diverting ileostomy at the Division of General and Hepatobiliary Surgery, University of Verona Hospital Trust between September 2015 and December 2016 were retrospectively analyzed. Of 15 patients, 10 patients underwent laparoscopic LAR and 5 patients a robot-assisted procedure. Post-operative complications were observed in 5 patients. Four patients suffered Clavien-Dindo grade 1 or 2 complications, and one patient required redo surgery due to bowel obstruction at the ileostomy site (grade 3b). Following ileostomy reversal, 10 out of 15 patients experienced complications. Two patients required redo surgery for bowel obstruction (grade 3b), whilst eight patients suffered grade 1 or 2 complications, being surgical site infection the most frequently observed (6 cases). Despite that, 80% of patients had their ileostomy reversed within 30 days and median time from initial surgery to ileostomy reversal was 22 days (range 10–150). Early ileostomy closure after minimally invasive LAR and ERAS program is feasible although it carries non-negligible risk of severe complications which, however, does not hinder its accomplishment.
Literature
4.
go back to reference Zhang W, Lou Z, Liu Q, Meng R, Gong H, Hao L, Liu P, Sun G, Ma J, Zhang W (2017) Multicenter analysis of risk factors for anastomotic leakage after middle and low rectal cancer resection without diverting stoma: a retrospective study of 319 consecutive patients. Int J Colorectal Dis. https://doi.org/10.1007/s00384-017-2875-8 Zhang W, Lou Z, Liu Q, Meng R, Gong H, Hao L, Liu P, Sun G, Ma J, Zhang W (2017) Multicenter analysis of risk factors for anastomotic leakage after middle and low rectal cancer resection without diverting stoma: a retrospective study of 319 consecutive patients. Int J Colorectal Dis. https://​doi.​org/​10.​1007/​s00384-017-2875-8
8.
go back to reference Chude GG, Rayate NV, Patris V, Koshariya M, Jagad R, Kawamoto J, Lygidakis NJ (2008) Defunctioning loop ileostomy with low anterior resection for distal rectal cancer: should we make an ileostomy as a routine procedure? A prospective randomized study. Hepatogastroenterology 55:1562–1567PubMed Chude GG, Rayate NV, Patris V, Koshariya M, Jagad R, Kawamoto J, Lygidakis NJ (2008) Defunctioning loop ileostomy with low anterior resection for distal rectal cancer: should we make an ileostomy as a routine procedure? A prospective randomized study. Hepatogastroenterology 55:1562–1567PubMed
10.
go back to reference Robertson JP, Puckett J, Vather R, Jaung R, Bissett I (2015) Early closure of temporary loop ileostomies: a systematic review. Ostomy Wound Manag 61:50–57 Robertson JP, Puckett J, Vather R, Jaung R, Bissett I (2015) Early closure of temporary loop ileostomies: a systematic review. Ostomy Wound Manag 61:50–57
11.
go back to reference Li W, Stocchi L, Cherla D, Liu G, Agostinelli A, Delaney CP, Steele SR, Gorgun E (2017) Factors associated with hospital readmission following diverting ileostomy creation. Tech Coloproctol. https://doi.org/10.1007/s10151-017-1667-z Li W, Stocchi L, Cherla D, Liu G, Agostinelli A, Delaney CP, Steele SR, Gorgun E (2017) Factors associated with hospital readmission following diverting ileostomy creation. Tech Coloproctol. https://​doi.​org/​10.​1007/​s10151-017-1667-z
12.
go back to reference Silva MA, Ratnayake G, Deen KI (2003) Quality of life of stoma patients: temporary ileostomy versus colostomy. World J Surg 27:421–424CrossRefPubMed Silva MA, Ratnayake G, Deen KI (2003) Quality of life of stoma patients: temporary ileostomy versus colostomy. World J Surg 27:421–424CrossRefPubMed
13.
go back to reference Brown H, Randle J (2005) Living with a stoma: a review of the literature. J Clin Nurs 14:74–81 (Review) CrossRefPubMed Brown H, Randle J (2005) Living with a stoma: a review of the literature. J Clin Nurs 14:74–81 (Review) CrossRefPubMed
16.
go back to reference Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Järvinen HJ (1997) A randomised study of colostomies in low colorectal anastomoses. Eur J Surg 163:929–933PubMed Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Järvinen HJ (1997) A randomised study of colostomies in low colorectal anastomoses. Eur J Surg 163:929–933PubMed
18.
go back to reference Pedrazzani C, Menestrina N, Moro M, Brazzo G, Mantovani G, Polati E, Guglielmi A (2016) Local wound infiltration plus transversus abdominis plane (TAP) block versus local wound infiltration in laparoscopic colorectal surgery and ERAS program. Surg Endosc 30:5117–5125CrossRefPubMed Pedrazzani C, Menestrina N, Moro M, Brazzo G, Mantovani G, Polati E, Guglielmi A (2016) Local wound infiltration plus transversus abdominis plane (TAP) block versus local wound infiltration in laparoscopic colorectal surgery and ERAS program. Surg Endosc 30:5117–5125CrossRefPubMed
19.
go back to reference Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
20.
go back to reference Rahbari NN, Weitz J, Hohenberger W, Heald RJ, Moran B, Ulrich A, Holm T, Wong WD, Tiret E, Moriya Y, Laurberg S, den Dulk M, van de Velde C, Büchler MW (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147:339–351. https://doi.org/10.1016/j.surg.2009.10.012 (Review) CrossRefPubMed Rahbari NN, Weitz J, Hohenberger W, Heald RJ, Moran B, Ulrich A, Holm T, Wong WD, Tiret E, Moriya Y, Laurberg S, den Dulk M, van de Velde C, Büchler MW (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147:339–351. https://​doi.​org/​10.​1016/​j.​surg.​2009.​10.​012 (Review) CrossRefPubMed
21.
go back to reference Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR (1999) Guideline for prevention of surgical site infection. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 20:250–278CrossRefPubMed Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR (1999) Guideline for prevention of surgical site infection. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 20:250–278CrossRefPubMed
22.
go back to reference Delaney CP, Kehlet H, Senagore AJ, Bauer AJ, Beart R, Billingham R, Coleman RL, Dozois EJ, Leslie JB, Marks J, Megibow AJ, Michelassi F, Steinbrook RA, On behalf of the Postoperative Ileus Management Council (PIMC) (2006) Postoperative ileus: profiles, risk factors and definitions. A framework for optimizing surgical outcomes in patients undergoing major abdominal and colorectal surgery. Clinical consensus update in general surgery. http://www.clinicalwebcasts.com/pdfs/GenSurg_WEB.pdf. Accessed 12 Dec 2013 Delaney CP, Kehlet H, Senagore AJ, Bauer AJ, Beart R, Billingham R, Coleman RL, Dozois EJ, Leslie JB, Marks J, Megibow AJ, Michelassi F, Steinbrook RA, On behalf of the Postoperative Ileus Management Council (PIMC) (2006) Postoperative ileus: profiles, risk factors and definitions. A framework for optimizing surgical outcomes in patients undergoing major abdominal and colorectal surgery. Clinical consensus update in general surgery. http://​www.​clinicalwebcasts​.​com/​pdfs/​GenSurg_​WEB.​pdf. Accessed 12 Dec 2013
23.
go back to reference Bakx R, Busch OR, van Geldere D, Bemelman WA, Slors JF, van Lanschot JJ (2003) Feasibility of early closure of loop ileostomies: a pilot study. Dis Colon Rectum 46:1680–1684CrossRefPubMed Bakx R, Busch OR, van Geldere D, Bemelman WA, Slors JF, van Lanschot JJ (2003) Feasibility of early closure of loop ileostomies: a pilot study. Dis Colon Rectum 46:1680–1684CrossRefPubMed
28.
go back to reference Robertson I, Leung E, Hughes D, Spiers M, Donnelly L, Mackenzie I, Macdonald A (2005) Prospective analysis of stoma-related complications. Colorectal Dis 7:279–285CrossRefPubMed Robertson I, Leung E, Hughes D, Spiers M, Donnelly L, Mackenzie I, Macdonald A (2005) Prospective analysis of stoma-related complications. Colorectal Dis 7:279–285CrossRefPubMed
37.
go back to reference Jordi-Galais P, Turrin N, Tresallet C, Nguyen-Thanh Q, Chigot JP, Menegaux F (2003) Early closure of temporary stoma of the small bowel. Gastroenterol Clin Biol 27:697–699 (French) PubMed Jordi-Galais P, Turrin N, Tresallet C, Nguyen-Thanh Q, Chigot JP, Menegaux F (2003) Early closure of temporary stoma of the small bowel. Gastroenterol Clin Biol 27:697–699 (French) PubMed
39.
go back to reference Hindenburg T, Rosenberg J (2010) Closing a temporary ileostomy within two weeks. Dan Med Bull 57:A4157 (Review) PubMed Hindenburg T, Rosenberg J (2010) Closing a temporary ileostomy within two weeks. Dan Med Bull 57:A4157 (Review) PubMed
40.
go back to reference Perdawid SK, Andersen OB (2011) Acceptable results of early closure of loop ileostomy to protect low rectal anastomosis. Dan Med Bull 58:A4280PubMed Perdawid SK, Andersen OB (2011) Acceptable results of early closure of loop ileostomy to protect low rectal anastomosis. Dan Med Bull 58:A4280PubMed
42.
go back to reference Rathnayake MM, Kumarage SK, Wijesuriya SR, Munasinghe BN, Ariyaratne MH, Deen KI (2008) Complications of loop ileostomy and ileostomy closure and their implications for extended enterostomal therapy: a prospective clinical study. Int J Nurs Stud 45:1118–1121 Epub 2007 Dec 21 CrossRefPubMed Rathnayake MM, Kumarage SK, Wijesuriya SR, Munasinghe BN, Ariyaratne MH, Deen KI (2008) Complications of loop ileostomy and ileostomy closure and their implications for extended enterostomal therapy: a prospective clinical study. Int J Nurs Stud 45:1118–1121 Epub 2007 Dec 21 CrossRefPubMed
Metadata
Title
Early ileostomy reversal after minimally invasive surgery and ERAS program for mid and low rectal cancer
Authors
Corrado Pedrazzani
Federica Secci
Eduardo Fernandes
Ivans Jelovskijs
Giulia Turri
Cristian Conti
Andrea Ruzzenente
Alfredo Guglielmi
Publication date
01-09-2019
Publisher
Springer International Publishing
Published in
Updates in Surgery / Issue 3/2019
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-018-0597-2

Other articles of this Issue 3/2019

Updates in Surgery 3/2019 Go to the issue