Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
The Journal of Obstetrics and Gynecology of India
Published in: The Journal of Obstetrics and Gynecology of India 6/2019

01-12-2019 | Thrombocytopenia | Guest Editorial

Coagulopathies in Pregnancy: What an Obstetrician Ought to Know!

Author: Abhay A. Bhave

Published in: The Journal of Obstetrics and Gynecology of India | Issue 6/2019

Login to get access

Excerpt

It is a matter of concern if you read “33 women die every hour from pregnancy and childbirth complications - India among 10 nations with highest maternal mortality ratio” (WHO). Complications of pregnancy and childbirth are the leading causes of disability and death amongst women between the ages of 15 and 49. In a study conducted in Mumbai, more than half of the women suffer from various complications and were in the younger age hailing from rural areas [1]. …
Literature
1.
Gogoi M. Pregnancy complications and birth outcome: do health care services make a difference? Int Res J Soc Sci. 2015; 4(3):27–35.
2.
Bolte AC, Hermans FJ, Van Rheenen-Flach LE. [227-POS]: Thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) in pregnancy: a systematic review. Pregnancy Hypertens Int J Women's Cardiovascular Health.. 2015;5(1):114–5.
3.
Levi M. Disseminated intravascular coagulation (DIC) in pregnancy and the peri-partum period. Thromb Res. 2009;1(123):S63–S6464.CrossRef
4.
Erez O, Mastrolia SA, Thachil J. Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management. Am J Obstet Gynecol. 2015;213(4):452–63.CrossRef
5.
Cortet M, Deneux-Tharaux C, Dupont C, Colin C, Rudigoz RC, Bouvier-Colle MH, Huissoud C. Association between fibrinogen level and severity of postpartum haemorrhage: secondary analysis of a prospective trial. Br J Anaesth. 2012;108(6):984–9.CrossRef
6.
Gupta M, Feinberg BB, Burwick RM. Thrombotic microangiopathies of pregnancy: differential diagnosis. Pregnancy hypertension. 2018;1(12):29–34.CrossRef
7.
8.
American College of Obstetricians and Gynecologists. Task Force on Hypertension in Pregnancy Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ task force on hypertension in pregnancy. Obstet Gynecol. 2013 Nov;122(5):1122–31.
9.
Furlan M, Robles R, Solenthaler M, Wassmer M, Sandoz P, Lämmle B. Deficient activity of von Willebrand factor–cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood. 1997;89(9):3097–103.CrossRef
10.
Peyvandi F, Lavoretano S, Palla R, Feys HB, Vanhoorelbeke K, Battaglioli T, Valsecchi C, Canciani MT, Fabris F, Zver S, Réti M. ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission. Haematologica. 2008; 93(2):232–9.CrossRef
11.
Benhamou Y, Baudel JL, Wynckel A, Galicier L, Azoulay E, Provôt F, Pène F, Mira JP, Presne C, Poullin P, Halimi JM. Are platelet transfusions harmful in acquired thrombotic thrombocytopenic purpura at the acute phase? Experience of the French thrombotic microangiopathies reference center. Am J Hematol. 2015;90(6):E127–E129129.CrossRef
12.
N. James, A.C. George, Acquired TTP: Clinical Manifestations and Diagnosis, in: L.L. Leung(Ed.), UpToDate,UpToDate,Waltham, MA, 2017. Accessed on 22 Nov 2017
13.
Bruel A, Kavanagh D, Noris M, Delmas Y, Wong EK, Bresin E, Provôt F, Brocklebank V, Mele C, Remuzzi G, Loirat C. Hemolytic uremic syndrome in pregnancy and postpartum. Clin J Am Soc Nephrol. 2017;12(8):1237–47.CrossRef
14.
Chan WS, Lee A, Spencer FA, Chunilal S, Crowther M, Wu W, Johnston M, Rodger M, Ginsberg JS. D-dimer testing in pregnant patients: towards determining the next ‘level’ in the diagnosis of deep vein thrombosis. J Thromb Haemost. 2010;8(5):1004–111.PubMed
15.
Kuriya A, Piedimonte S, Spence AR, Czuzoj-Shulman N, Kezouh A, Abenhaim HA. Incidence and causes of maternal mortality in the USA. J Obstet Gynaecol Res. 2016;42(6):661–8.CrossRef
16.
Leonhardt G, Gaul C, Nietsch HH, Buerke M, Schleussner E. Thrombolytic therapy in pregnancy. J Thromb Thrombolysis. 2006;21(3):271–6.CrossRef
17.
Forestier F, Daffos F, Capella-Pavlovsky M. Low molecular weight heparin (PK 10169) does not cross the placenta during the second trimester of pregnancy study by direct fetal blood sampling under ultrasound. Thromb Res. 1984;34(6):557–60.CrossRef
18.
Kamel H, Navi BB, Sriram N, Hovsepian DA, Devereux RB, Elkind MS. Risk of a thrombotic event after the 6-week postpartum period. N Engl J Med. 2014;370(14):1307–15.CrossRef
19.
Blondon M, Casini A, Hoppe KK, Boehlen F, Righini M, Smith NL. Risks of venous thromboembolism after cesarean sections: a meta-analysis. Chest. 2016;150(3):572–96.CrossRef
Metadata
Title
Coagulopathies in Pregnancy: What an Obstetrician Ought to Know!
Author
Abhay A. Bhave
Publication date
01-12-2019
Publisher
Springer India
Published in
The Journal of Obstetrics and Gynecology of India / Issue 6/2019
Print ISSN: 0971-9202
Electronic ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-019-01290-8

Other articles of this Issue 6/2019

The Journal of Obstetrics and Gynecology of India 6/2019 Go to the issue

Original Article

Association Between Fetal Middle Cerebral Artery and Umbilical Artery Doppler Ratio with Fetal Distress in 38–40 Weeks of Gestation

Original Article

Bilateral Internal Iliac Artery Ligation, a Rational Choice of Surgery in Placenta Previa, a Hospital-Based Retrospective Study on the Prevention of Hysterectomy and Control of Postpartum Hemorrhage

Review Article

Rising Cesarean Rates: Are Primary Sections Overused?

Original Article

Impact of Community-Based Continuous Training on Promoting Birth Preparedness and Pregnancy Outcome in Rural Odisha, India: An Interventional Study

Short Commentary

Caesarean Delivery in the Second Stage of Labour at a Tertiary Care Hospital

Case Report

Partial Molar Pregnancy Associated with Severely Anemic Singleton Pregnancy