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Nuclear Medicine and Molecular Imaging
Published in: Nuclear Medicine and Molecular Imaging 1/2021

01-02-2021 | Magnetic Resonance Imaging | Case Report

Imaging Characteristics of Brain SPECT, PET, and MRI in Neurosyphilis

Authors: Eun Kyoung Choi, Young Do Kim, Hyeonseok Jeong, Yong-An Chung, Jin Kyoung Oh, In-Uk Song

Published in: Nuclear Medicine and Molecular Imaging | Issue 1/2021

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Abstract

The incidence of neurosyphilis has declined since effective penicillin therapy against Treponema pallidum was introduced. However, the diagnosis of neurosyphilis early in the disease course is very important in order to select appropriate antibiotic therapy. We report brain MRI, SPECT with Tc-99m ECD, and PET with F-18 FDG findings before antibiotic therapy in a neurosyphilis patient with neurological symptoms. The cerebral cortices showed hypoperfusion with a patchy distribution on SPECT and foci with high signal intensity on MRI, suggesting ischemia. Brain PET showed areas with hypometabolism in the temporoparietal lobes bilaterally.
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Metadata
Title
Imaging Characteristics of Brain SPECT, PET, and MRI in Neurosyphilis
Authors
Eun Kyoung Choi
Young Do Kim
Hyeonseok Jeong
Yong-An Chung
Jin Kyoung Oh
In-Uk Song
Publication date
01-02-2021
Publisher
Springer Singapore
Published in
Nuclear Medicine and Molecular Imaging / Issue 1/2021
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-021-00684-9

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