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01-02-2013 | Original Article

Genetic Animal Models of Preconditioning

Authors: Priti Azad, Gabriel G. Haddad

Published in: Translational Stroke Research | Issue 1/2013

Abstract

The preconditioning phenomena have been well established in the heart as well as in the brain. In this review, we detail some of the original studies on preconditioning as well as studies from our lab using rodents and a genetic model system (fruit fly). We have used Drosophila in our lab to solve some of the questions related to tolerance or susceptibility to hypoxia. We believe that these pro-survival strategies and genetic pathways help us understand some of the preconditioning mechanisms that protect the brain from ischemia.

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Title: Genetic Animal Models of Preconditioning
Authors: Priti Azad
Gabriel G. Haddad
Publication date: 01-02-2013
Publisher: Springer US
Published in: Translational Stroke Research / Issue 1/2013
Print ISSN: 1868-4483
Electronic ISSN: 1868-601X
DOI: https://doi.org/10.1007/s12975-012-0218-1

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