An occurrence of clinical eperythrozoonosis in a German Shepherd dog and its therapeutic management

Eperythrozoon spp.–a rickettsial (Mycoplasma) pathogen of the mammalian erythrocytic cell membrane, has been recognised to cause non specific, sporadic, febrile and haemolytic clinical disease in a variety of livestock, especially food animals. However, clinical eperythrozoonosis in companion animals seems not documented so far. An adult male German shepherd dog, aged 10.5 years and weighing 45 kg with clinical history of persistent mild fever in morning hours, depression and anorexia for the past 5 days and nasal bleeding for the past few months, was presented to clinicians for therapeutic management. Microscopic examination of Giemsa stained blood smear evidenced characteristic light pinkish to blue stained cocci and/or short rod shaped pathogens identified as Eperythrozoon canis, nesting in the depressions on the periphery of erythrocyte cell membrane as well as extra cellular free bodies in the plasma. Rhinoscopic detailed investigation failed to demonstrate any lesion in the nasal passage that could be attributed to the frequent nasal bleeding for the past few months. The dog was subsequently therapeutically managed with success using specific therapy and followed by supportive therapy. Finally, the predisposing factors of the disease, reasons for frequent nasal bleeding, clinical course of the disease in canines and its public health significance vis-à-vis future projections have been discussed.