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Published in: international journal of stomatology & occlusion medicine 1/2016

01-09-2016 | original article

Polyvinylpyrrolidone-iodine 2 % as hemostyptic agent in routine dental extraction

Authors: Kanwaldeep Singh Soodan, Nageshwar Iyer, Pratiksha Priyadarshni, Vasit Khajuria

Published in: international journal of stomatology & occlusion medicine | Special Issue 1/2016

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Abstract

Objective

The aim of this study was to evaluate the effect of polyvinylpyrrolidone-iodine (PVP-I) 2 % as hemostyptic when used as an irrigant in low concentration during surgical procedures.

Methods

We selected 100 healthy patients who needed routine dental extraction for this study. Patients were divided into two groups: the treatment group (n = 50) and the control group (n = 50). The alveolar sockets of patients in the treatment group were irrigated using PVP-I (2 %, w/v) following routine dental extraction, whereas those of the control group were irrigated using normal saline (sodium chloride 0.9 %, w/v). Spontaneous cessation of bleeding from the socket following irrigation was considered as significant hemostasis. After irrigation, the sockets were compressed with digital pressure. Data were analyzed using SPSS software.

Results

Both groups were matched for age (t test, p > 0.05 %). Average bleeding control time in the PVP-I (2 % w/v) group was 135.72 ± 11.348 s and in the saline group 168.78 ± 23.661 s (which was statistically significant at p < 0.001). Out of 100 patients, 42 % were female and 58 % were male; both groups were matched for gender (χ2, p = 0.224).

Conclusion

PVP-I significantly (p < 0.001) controlled bleeding as compared with saline, suggesting that PVP-I irrigation acts as a hemostyptic.
Literature
1.
go back to reference Garnes AL, Davidson E, Taylor LE, Felix AJ, Shidlovsky BA, Prigot A. Clinical evaluation of Povidone-iodine aerosol spray in surgical practice. Am J Surg. 1959;97(1):49–53.CrossRefPubMed Garnes AL, Davidson E, Taylor LE, Felix AJ, Shidlovsky BA, Prigot A. Clinical evaluation of Povidone-iodine aerosol spray in surgical practice. Am J Surg. 1959;97(1):49–53.CrossRefPubMed
2.
go back to reference Posner AC, Cordice JW Jr, Scudder J. Effect of polyvinylpyrrolidone in obstetrical cases. Surg Gynecol Obstet. 1953;96(5):581–3.PubMed Posner AC, Cordice JW Jr, Scudder J. Effect of polyvinylpyrrolidone in obstetrical cases. Surg Gynecol Obstet. 1953;96(5):581–3.PubMed
3.
go back to reference Cordice JW Jr, Scudder J. Polyvinylpyrrolidone in the treatment of traumatic and hemorrhagic shock and severe burns. N Y State J Med. 1954;54(5):652–8.PubMed Cordice JW Jr, Scudder J. Polyvinylpyrrolidone in the treatment of traumatic and hemorrhagic shock and severe burns. N Y State J Med. 1954;54(5):652–8.PubMed
4.
go back to reference Shelanski HA, Shelanski MV. PVP iodine: history, toxicity and therapeutic uses. J Int Coll Surg. 1956;25(6):727–4.PubMed Shelanski HA, Shelanski MV. PVP iodine: history, toxicity and therapeutic uses. J Int Coll Surg. 1956;25(6):727–4.PubMed
5.
go back to reference Siggia S. The chemistry of Polyvinylpyrrolidone-iodine. J Am Pharm Assoc Am Pharm Assoc. 1957;46(3):201–4.CrossRefPubMed Siggia S. The chemistry of Polyvinylpyrrolidone-iodine. J Am Pharm Assoc Am Pharm Assoc. 1957;46(3):201–4.CrossRefPubMed
7.
go back to reference Chundamala J, Wright JG. The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence based review. Can J Surg. 2007;50(6):473–1.PubMedPubMedCentral Chundamala J, Wright JG. The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence based review. Can J Surg. 2007;50(6):473–1.PubMedPubMedCentral
8.
go back to reference Kumar BP, Maddi A, Ramesh KV, et al. Is povidone iodine a hemostyptic? A clinical study. Int J Oral Maxillofac Surg. 2006;35(8):765–6.CrossRefPubMed Kumar BP, Maddi A, Ramesh KV, et al. Is povidone iodine a hemostyptic? A clinical study. Int J Oral Maxillofac Surg. 2006;35(8):765–6.CrossRefPubMed
9.
go back to reference Beukelman CJ, van den Berg AJ, Hoekstra MJ, et al. Anti-inflammatory properties of a liposomal hydrogel with povidone iodine (Repithell) for wound healing in vitro. Burns. 2008;34(6):845–5.CrossRefPubMed Beukelman CJ, van den Berg AJ, Hoekstra MJ, et al. Anti-inflammatory properties of a liposomal hydrogel with povidone iodine (Repithell) for wound healing in vitro. Burns. 2008;34(6):845–5.CrossRefPubMed
10.
go back to reference Zamora JL. Chemical and microbiologic characteristics and toxicity of Povidone iodine Solutions. Am J Surg. 1986;151(3):400–6.CrossRefPubMed Zamora JL. Chemical and microbiologic characteristics and toxicity of Povidone iodine Solutions. Am J Surg. 1986;151(3):400–6.CrossRefPubMed
11.
go back to reference Kumar KS, Reddy GV, Naidu G, Pandiarajan R. Role of povidone iodine in periapical surgeries: Hemostyptic and anti-inflammatory? Ann Maxillofac Surg. 2011;1(2):107–1.CrossRefPubMedPubMedCentral Kumar KS, Reddy GV, Naidu G, Pandiarajan R. Role of povidone iodine in periapical surgeries: Hemostyptic and anti-inflammatory? Ann Maxillofac Surg. 2011;1(2):107–1.CrossRefPubMedPubMedCentral
Metadata
Title
Polyvinylpyrrolidone-iodine 2 % as hemostyptic agent in routine dental extraction
Authors
Kanwaldeep Singh Soodan
Nageshwar Iyer
Pratiksha Priyadarshni
Vasit Khajuria
Publication date
01-09-2016
Publisher
Springer Vienna
Published in
international journal of stomatology & occlusion medicine / Issue Special Issue 1/2016
Print ISSN: 1867-2221
Electronic ISSN: 1867-223X
DOI
https://doi.org/10.1007/s12548-016-0145-y

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