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international journal of stomatology & occlusion medicine
Published in: international journal of stomatology & occlusion medicine 1/2016

01-09-2016 | review

Dental pulp regeneration

In vitro and in vivo approaches

Authors: Klara Janjić, Barbara Cvikl, Andreas Moritz, Hermann Agis

Published in: international journal of stomatology & occlusion medicine | Special Issue 1/2016

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Abstract

Trauma in the oral region and tooth avulsion are a major part of injuries in children, adolescents, and young adults. Established methods used to manage these cases provide mainly repair, but not regeneration. Tissue engineering paves the way for research in the new field of regenerative endodontics to overcome the limits of conservative strategies. This review aims to provide an overview of the available in vitro and in vivo models for dental pulp regeneration. The review covers different in vitro models, including two- and three-dimensional models and organ cultures, comprising both ectopic and orthotopic approaches. These models show the great potential of tissue engineering for regenerative endodontics, which can lead to regeneration of the pulp–dentin complex in future.
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Metadata
Title
Dental pulp regeneration
In vitro and in vivo approaches
Authors
Klara Janjić
Barbara Cvikl
Andreas Moritz
Hermann Agis
Publication date
01-09-2016
Publisher
Springer Vienna
Published in
international journal of stomatology & occlusion medicine / Issue Special Issue 1/2016
Print ISSN: 1867-2221
Electronic ISSN: 1867-223X
DOI
https://doi.org/10.1007/s12548-015-0139-1

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