Top

Published in:

Open Access 01-08-2012 | Intravascular Imaging (U Landmesser, Section Editor)

Optical Coherence Tomography: Potential Clinical Applications

Authors: Antonios Karanasos, Jurgen Ligthart, Karen Witberg, Gijs van Soest, Nico Bruining, Evelyn Regar

Published in: Current Cardiovascular Imaging Reports | Issue 4/2012

Abstract

Optical coherence tomography (OCT) is a novel intravascular imaging modality using near-infrared light. By OCT it is possible to obtain high-resolution cross-sectional images of the vascular wall structure and assess the acute and long-term effects of percutaneous coronary intervention. For the time being OCT has been mainly used in research providing new insights into the pathophysiology of the atheromatic plaque and of the vascular response to stenting, however, it seems that there is potential for clinical application of OCT in various fields, such as pre-interventional evaluation of coronary arteries, procedural guidance in coronary interventions, and follow-up assessment of vascular healing after stent implantation. This review will focus on the potential and advantages of OCT in the clinical practice of a catheterization laboratory.

Garcia-Garcia HM, Gonzalo N, Kukreja N, Alfonso F. Greyscale intravascular ultrasound and IVUS-radiofrequency tissue characterisation to improve understanding of the mechanisms of coronary stent thrombosis in drug-eluting stents. EuroIntervention. 2008;4(Suppl C):C33–8.PubMed

Choi SY, Witzenbichler B, Maehara A, Lansky AJ, Guagliumi G, Brodie B, et al. Intravascular ultrasound findings of early stent thrombosis after primary percutaneous intervention in acute myocardial infarction: a Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) substudy. Circ Cardiovasc Interv. 2011;4(3):239–47.PubMedCrossRef

Liu X, Doi H, Maehara A, Mintz GS, de Ribamar Costa Jr J, Sano K, et al. A volumetric intravascular ultrasound comparison of early drug-eluting stent thrombosis versus restenosis. JACC Cardiovasc Interv. 2009;2(5):428–34.PubMedCrossRef

Nissen SE, Nicholls SJ, Sipahi I, Libby P, Raichlen JS, Ballantyne CM, et al. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006;295(13):1556–65.PubMedCrossRef

Serruys PW, Garcia-Garcia HM, Buszman P, Erne P, Verheye S, Aschermann M, et al. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation. 2008;118(11):1172–82.PubMedCrossRef

Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, et al. A prospective natural-history study of coronary atherosclerosis. N Engl J Med. 2011;364(3):226–35.PubMedCrossRef

•• Tearney GJ, Regar E, Akasaka T, Adriaenssens T, Barlis P, Bezerra HG, et al. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the international working group for intravascular optical coherence tomography standardization and validation. J Am Coll Cardiol. 2012;59(12):1058–72. This is a consensus document that can be broadly used as a standard reference regarding the current state of the IVOCT imaging modality.PubMedCrossRef

Takarada S, Imanishi T, Liu Y, Ikejima H, Tsujioka H, Kuroi A, et al. Advantage of next-generation frequency-domain optical coherence tomography compared with conventional time-domain system in the assessment of coronary lesion. Catheter Cardiovasc Interv. 2010;75(2):202–6.PubMedCrossRef

Bouma BE, Tearney GJ, Yabushita H, Shishkov M, Kauffman CR, DeJoseph Gauthier D, et al. Evaluation of intracoronary stenting by intravascular optical coherence tomography. Heart. 2003;89(3):317–20.PubMedCrossRef

10.

Prati F, Cera M, Ramazzotti V, Imola F, Giudice R, Albertucci M. Safety and feasibility of a new non-occlusive technique for facilitated intracoronary optical coherence tomography (OCT) acquisition in various clinical and anatomical scenarios. EuroIntervention. 2007;3(3):365–70.PubMedCrossRef

11.

•• Barlis P, Gonzalo N, Di Mario C, Prati F, Buellesfeld L, Rieber J, et al. A multicentre evaluation of the safety of intracoronary optical coherence tomography. EuroIntervention. 2009;5(1):90–5. This is the first systematic attempt to evaluate the safety of OCT.PubMedCrossRef

12.

Imola F, Mallus MT, Ramazzotti V, Manzoli A, Pappalardo A, Di Giorgio A, et al. Safety and feasibility of frequency domain optical coherence tomography to guide decision making in percutaneous coronary intervention. EuroIntervention. 2010;6(5):575–81.PubMedCrossRef

13.

Kume T, Akasaka T, Kawamoto T, Watanabe N, Toyota E, Neishi Y, et al. Assessment of coronary intima–media thickness by optical coherence tomography: comparison with intravascular ultrasound. Circ J. 2005;69(8):903–7.PubMedCrossRef

14.

Yabushita H, Bouma BE, Houser SL, Aretz HT, Jang IK, Schlendorf KH, et al. Characterization of human atherosclerosis by optical coherence tomography. Circulation. 2002;106(13):1640–5.PubMedCrossRef

15.

Kume T, Akasaka T, Kawamoto T, Ogasawara Y, Watanabe N, Toyota E, et al. Assessment of coronary arterial thrombus by optical coherence tomography. Am J Cardiol. 2006;97(12):1713–7.PubMedCrossRef

16.

Murata A, Wallace-Bradley D, Tellez A, Alviar C, Aboodi M, Sheehy A, et al. Accuracy of optical coherence tomography in the evaluation of neointimal coverage after stent implantation. JACC Cardiovasc Imaging. 2010;3(1):76–84.PubMedCrossRef

17.

Gonzalo N, Serruys PW, Garcia-Garcia HM, van Soest G, Okamura T, Ligthart J, et al. Quantitative ex vivo and in vivo comparison of lumen dimensions measured by optical coherence tomography and intravascular ultrasound in human coronary arteries. Rev Esp Cardiol. 2009;62(6):615–24.PubMedCrossRef

18.

Gonzalo N, Garcia-Garcia HM, Serruys PW, Commissaris KH, Bezerra H, Gobbens P, et al. Reproducibility of quantitative optical coherence tomography for stent analysis. EuroIntervention. 2009;5(2):224–32.PubMedCrossRef

19.

Tahara S, Bezerra HG, Baibars M, Kyono H, Wang W, Pokras S, et al. In vitro validation of new Fourier-domain optical coherence tomography. EuroIntervention. 2011;6(7):875–82.PubMedCrossRef

20.

Okamura T, Gonzalo N, Gutierrez-Chico JL, Serruys PW, Bruining N, de Winter S, et al. Reproducibility of coronary Fourier domain optical coherence tomography: quantitative analysis of in vivo stented coronary arteries using three different software packages. EuroIntervention. 2010;6(3):371–9.PubMedCrossRef

21.

Sihan K, Botha C, Post F, de Winter S, Gonzalo N, Regar E, et al. Fully automatic three-dimensional quantitative analysis of intracoronary optical coherence tomography: method and Validation. Catheter Cardiovasc Interv. 2009;74(7):1058–65.PubMedCrossRef

22.

Tanimoto S, Rodriguez-Granillo G, Barlis P, de Winter S, Bruining N, Hamers R, et al. A novel approach for quantitative analysis of intracoronary optical coherence tomography: high inter-observer agreement with computer-assisted contour detection. Catheter Cardiovasc Interv. 2008;72(2):228–35.PubMedCrossRef

23.

Mintz GS, Painter JA, Pichard AD, Kent KM, Satler LF, Popma JJ, et al. Atherosclerosis in angiographically normal coronary-artery reference segments - an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol. 1995;25(7):1479–85.PubMedCrossRef

24.

Tonino PA, De Bruyne B, Pijls NH, Siebert U, Ikeno F, van' t Veer M, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213–24.PubMedCrossRef

25.

Kang SJ, Lee JY, Ahn JM, Mintz GS, Kim WJ, Park DW, et al. Validation of intravascular ultrasound-derived parameters with fractional flow reserve for assessment of coronary stenosis severity. Circ Cardiovasc Interv. 2011;4(1):65–71.PubMedCrossRef

26.

Gonzalo N, Escaned J, Alfonso F, Nolte C, Rodriguez V, Jimenez-Quevedo P, et al. Morphometric assessment of coronary stenosis relevance with optical coherence tomography: a comparison with fractional flow reserve and intravascular ultrasound. J Am Coll Cardiol. 2012;59(12):1080–9.PubMedCrossRef

27.

Toutouzas K, Karanasos A, Stathogiannis K, Synetos A, Tsiamis E, Papadopoulos D, et al. A honeycomb-like structure in the left anterior descending coronary artery: demonstration of recanalized thrombus by optical coherence tomography. JACC Cardiovasc Interv. 2012; (in press).

28.

Toutouzas K, Karanasos A, Stefanadis C. Pitfalls of angiography in the assessment of atherosclerosis: The role of optical coherence tomography. J Invasive Cardiol. 2012; (in press).

29.

Alfonso F, Paulo M, Gonzalo N, Dutary J, Jimenez-Quevedo P, Lennie V, et al. Diagnosis of spontaneous coronary artery dissection by optical coherence tomography. J Am Coll Cardiol. 2012;59(12):1073–9.PubMedCrossRef

30.

Kubo T, Imanishi T, Takarada S, Kuroi A, Ueno S, Yamano T, et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J Am Coll Cardiol. 2007;50(10):933–9.PubMedCrossRef

31.

Tanaka A, Shimada K, Tearney GJ, Kitabata H, Taguchi H, Fukuda S, et al. Conformational change in coronary artery structure assessed by optical coherence tomography in patients with vasospastic angina. J Am Coll Cardiol. 2011;58(15):1608–13.PubMedCrossRef

32.

Stefano GT, Bezerra HG, Attizzani G, Chamie D, Mehanna E, Yamamoto H, et al. Utilization of frequency domain optical coherence tomography and fractional flow reserve to assess intermediate coronary artery stenoses: conciliating anatomic and physiologic information. Int J Cardiovasc Imaging. 2011;27(2):299–308.PubMedCrossRef

33.

Porto I, Di Vito L, Burzotta F, Niccoli G, Trani C, Leone AM, et al. Predictors of periprocedural (Type IVa) myocardial infarction, as assessed by frequency-domain optical coherence tomography. Circ Cardiovasc Interv. 2012;5(1):89–96.PubMedCrossRef

34.

Kubo T, Imanishi T, Kitabata H, Kuroi A, Ueno S, Yamano T, et al. Comparison of vascular response after sirolimus-eluting stent implantation between patients with unstable and stable angina pectoris: a serial optical coherence tomography study. JACC Cardiovasc Imaging. 2008;1(4):475–84.PubMedCrossRef

35.

Secco GG, Foin N, Viceconte N, Borgia F, De Luca G, Di Mario C. Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons. EuroIntervention. 2011;7(7):828–34.PubMedCrossRef

36.

Kume T, Okura H, Kawamoto T, Yamada R, Miyamoto Y, Hayashida A, et al. Assessment of the coronary calcification by optical coherence tomography. EuroIntervention. 2011;6(6):768–72.PubMedCrossRef

37.

• Viceconte N, Chan PH, Barrero EA, Ghilencea L, Lindsay A, Foin N, et al. Frequency domain optical coherence tomography for guidance of coronary stenting. Int J Cardiol. 2011. in press. A report on the use of OCT for interventional guidance.

38.

de Jaegere P, Mudra H, Figulla H, Almagor Y, Doucet S, Penn I, et al. Intravascular ultrasound-guided optimized stent deployment. Immediate and 6 months clinical and angiographic results from the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study). Eur Heart J. 1998;19(8):1214–23.PubMedCrossRef

39.

Toutouzas K, Karanasos A, Stefanadis C. Multiple plaque morphologies assessed by optical coherence tomography in a patient with acute coronary syndrome. Heart. 2010;96(16):1335–6.PubMedCrossRef

40.

• Toutouzas K, Karanasos A, Tsiamis E, Riga M, Drakopoulou M, Synetos A, et al. New insights by optical coherence tomography into the differences and similarities of culprit ruptured plaque morphology in non-ST-elevation myocardial infarction and ST-elevation myocardial infarction. Am Heart J. 2011;161(6):1192–9. This study highlights the significance of the longitudinal assessment of coronary plaques with implications in the landing zone concept.PubMedCrossRef

41.

Gonzalo N, Serruys PW, Okamura T, Shen ZJ, Garcia-Garcia HM, Onuma Y, et al. Relation between plaque type and dissections at the edges after stent implantation: an optical coherence tomography study. Int J Cardiol. 2011;150(2):151–5.PubMedCrossRef

42.

Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, et al. Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol. 2006;48(1):193–202.PubMedCrossRef

43.

Hetterich H, Redel T, Lauritsch G, Rohkohl C, Rieber J. New X-ray imaging modalities and their integration with intravascular imaging and interventions. Int J Cardiovasc Imaging. 2010;26(7):797–808.PubMedCrossRef

44.

Tu S, Holm NR, Koning G, Huang Z, Reiber JH. Fusion of 3D QCA and IVUS/OCT. Int J Cardiovasc Imaging. 2011;27(2):197–207.PubMedCrossRef

45.

Schultz C, van der Ent M, Serruys PW, Regar E. Optical coherence tomography to guide treatment of chronic occlusions? JACC Cardiovasc Interv. 2009;2(4):366–7.PubMedCrossRef

46.

Farooq V, Serruys PW, Heo JH, Gogas BD, Okamura T, Gomez-Lara J, et al. New insights into the coronary artery bifurcation hypothesis-generating concepts utilizing 3-dimensional optical frequency domain imaging. JACC Cardiovasc Interv. 2011;4(8):921–31.PubMedCrossRef

47.

Okamura T, Yamada J, Nao T, Suetomi T, Maeda T, Shiraishi K, et al. Three-dimensional optical coherence tomography assessment of coronary wire re-crossing position during bifurcation stenting. EuroIntervention. 2011;7(7):886–7.PubMedCrossRef

48.

• Tu S, Xu L, Ligthart J, Xu B, Witberg K, Sun Z, et al. In vivo comparison of arterial lumen dimensions assessed by co-registered three-dimensional (3D) quantitative coronary angiography, intravascular ultrasound and optical coherence tomography. Int J Cardiovasc Imaging. 2012. This study introduces a new software package for registration of angiography and OCT and for the online reconstruction of three-dimensional models.

49.

Farb A, Burke AP, Kolodgie FD, Virmani R. Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation. 2003;108(14):1701–6.PubMedCrossRef

50.

Kume T, Okura H, Miyamoto Y, Yamada R, Saito K, Tamada T, et al. Natural history of stent edge dissection, tissue protrusion and incomplete stent apposition detectable only on optical coherence tomography after stent implantation. Circ J. 2012. in press.

51.

• Gonzalo N, Serruys PW, Okamura T, Shen ZJ, Onuma Y, Garcia-Garcia HM, et al. Optical coherence tomography assessment of the acute effects of stent implantation on the vessel wall: a systematic quantitative approach. Heart. 2009;95(23):1913–9. A detailed description of acute vascular wall response to stenting.PubMedCrossRef

52.

Tanigawa J, Barlis P, Dimopoulos K, Dalby M, Moore P, Di Mario C. The influence of strut thickness and cell design on immediate apposition of drug-eluting stents assessed by optical coherence tomography. Int J Cardiol. 2009;134(2):180–8.PubMedCrossRef

53.

Ozaki Y, Okumura M, Ismail TF, Naruse H, Hattori K, Kan S, et al. The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study. Eur Heart J. 2010;31(12):1470–6.PubMedCrossRef

54.

Attizzani GF, Patricio L, Bezerra HG. Optical coherence tomography assessment of calcified plaque modification after rotational atherectomy. Catheter Cardiovasc Interv. 2011.

55.

Prati F, Capodanno D, Pawlowski T, Ramazzotti V, Albertucci M, La Manna A, et al. Local delivery versus intracoronary infusion of abciximab in patients with acute coronary syndromes. JACC Cardiovasc Interv. 2010;3(9):928–34.PubMedCrossRef

56.

Van Mieghem NM, Kauer F, Regar E. Rheolytic versus aspiration thrombectomy in acute st-segment elevation myocardial infarction judged by OCT. EuroIntervention. 2010;5(8):994.PubMedCrossRef

57.

Suzuki Y, Ikeno F, Koizumi T, Tio F, Yeung AC, Yock PG, et al. In vivo comparison between optical coherence tomography and intravascular ultrasound for detecting small degrees of in-stent neointima after stent implantation. JACC Cardiovasc Interv. 2008;1(2):168–73.PubMedCrossRef

58.

Templin C, Meyer M, Muller MF, Djonov V, Hlushchuk R, Dimova I, et al. Coronary optical frequency domain imaging (OFDI) for in vivo evaluation of stent healing: comparison with light and electron microscopy. Eur Heart J. 2010;31(14):1792–801.PubMedCrossRef

59.

Nakano M, Vorpahl M, Otsuka F, Taniwaki M, Yazdani SK, Finn AV, et al. Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging. JACC Cardiovasc Imaging. 2012;5(1):71–82.PubMedCrossRef

60.

Takano M, Inami S, Jang IK, Yamamoto M, Murakami D, Seimiya K, et al. Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent three months after implantation. Am J Cardiol. 2007;99(8):1033–8.PubMedCrossRef

61.

Takano M, Yamamoto M, Mizuno M, Murakami D, Inami T, Kimata N, et al. Late vascular responses from 2 to 4 years after implantation of sirolimus-eluting stents: serial observations by intracoronary optical coherence tomography. Circ Cardiovasc Interv. 2010;3(5):476–83.PubMedCrossRef

62.

Chen BX, Ma FY, Luo W, Ruan JH, Xie WL, Zhao XZ, et al. Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography. Heart. 2008;94(5):566–70.PubMedCrossRef

63.

Guagliumi G, Costa MA, Sirbu V, Musumeci G, Bezerra HG, Suzuki N, et al. Strut coverage and late malapposition with paclitaxel-eluting stents compared with bare metal stents in acute myocardial infarction: optical coherence tomography substudy of the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial. Circulation. 2011;123(3):274–81.PubMedCrossRef

64.

Guagliumi G, Sirbu V, Bezerra H, Biondi-Zoccai G, Fiocca L, Musumeci G, et al. Strut coverage and vessel wall response to zotarolimus-eluting and bare-metal stents implanted in patients with ST-segment elevation myocardial infarction: the OCTAMI (Optical Coherence Tomography in Acute Myocardial Infarction) Study. JACC Cardiovasc Interv. 2010;3(6):680–7.PubMedCrossRef

65.

Kim JS, Kim JS, Kim TH, Fan C, Lee JM, Kim W, et al. Comparison of neointimal coverage of sirolimus-eluting stents and paclitaxel-eluting stents using optical coherence tomography at 9 months after implantation. Circ J. 2010;74(2):320–6.PubMedCrossRef

66.

Gutierrez-Chico JL, van Geuns RJ, Regar E, van der Giessen WJ, Kelbaek H, Saunamaki K, et al. Tissue coverage of a hydrophilic polymer-coated zotarolimus-eluting stent vs. a fluoropolymer-coated everolimus-eluting stent at 13-month follow-up: an optical coherence tomography substudy from the RESOLUTE All Comers trial. Eur Heart J. 2011;32(19):2454–63.PubMedCrossRef

67.

Synetos A, Toutouzas K, Karanasos A, Stathogiannis K, Triantafyllou G, Tsiamis E, et al. Differences in drug-eluting stents used in coronary artery disease. Am J Med Sci. 2011;342(5):402–8.PubMedCrossRef

68.

Inoue K, Abe K, Ando K, Shirai S, Nishiyama K, Nakanishi M, et al. Pathological analyses of long-term intracoronary Palmaz-Schatz stenting; Is its efficacy permanent? Cardiovasc Pathol. 2004;13(2):109–15.PubMedCrossRef

69.

Nakazawa G, Otsuka F, Nakano M, Vorpahl M, Yazdani SK, Ladich E, et al. The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents. J Am Coll Cardiol. 2011;57(11):1314–22.PubMedCrossRef

70.

Gonzalo N, Serruys PW, Okamura T, van Beusekom HM, Garcia-Garcia HM, van Soest G, et al. Optical coherence tomography patterns of stent restenosis. Am Heart J. 2009;158(2):284–93.PubMedCrossRef

71.

Tanimoto S, Aoki J, Serruys PW, Regar E. Paclitaxel-eluting stent restenosis shows three-layer appearance by optical coherence tomography. EuroIntervention. 2006;1(4):484.PubMed

72.

Guagliumi G, Sirbu V, Musumeci G, Gerber R, Biondi-Zoccai G, Ikejima H, et al. Examination of the in vivo mechanisms of late drug-eluting stent thrombosis: findings from optical coherence tomography and intravascular ultrasound imaging. JACC Cardiovasc Interv. 2012;5(1):12–20.PubMedCrossRef

73.

Yamaji K, Inoue K, Nakahashi T, Noguchi M, Domei T, Hyodo M, et al. Bare metal stent thrombosis and in-stent neoatherosclerosis. Circ Cardiovasc Interv. 2012;5(1):47–54.PubMedCrossRef

74.

Barlis P, Regar E, Serruys PW, Dimopoulos K, van der Giessen WJ, van Geuns RJ, et al. An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study. Eur Heart J. 2010;31(2):165–76.PubMedCrossRef

75.

Guagliumi G, Sirbu V, Musumeci G, Bezerra HG, Aprile A, Kyono H, et al. Strut coverage and vessel wall response to a new-generation paclitaxel-eluting stent with an ultrathin biodegradable abluminal polymer: Optical Coherence Tomography Drug-Eluting Stent Investigation (OCTDESI). Circ Cardiovasc Interv. 2010;3(4):367–75.PubMedCrossRef

76.

Prati F, Stazi F, Dutary J, La Manna A, Di Giorgio A, Pawlosky T, et al. Detection of very early stent healing after primary angioplasty: an optical coherence tomographic observational study of chromium cobaltum and first-generation drug-eluting stents. The DETECTIVE study. Heart. 2011;97(22):1841–6.PubMedCrossRef

77.

Gutierrez-Chico JL, van Geuns RJ, Koch KT, Koolen JJ, Duckers H, Regar E, et al. Paclitaxel-coated balloon in combination with bare metal stent for treatment of de novo coronary lesions: an optical coherence tomography first-in-human randomised trial, balloon first vs. stent first. EuroIntervention. 2011;7(6):711–22.PubMedCrossRef

78.

Slottow TL, Pakala R, Okabe T, Hellinga D, Lovec RJ, Tio FO, et al. Optical coherence tomography and intravascular ultrasound imaging of bioabsorbable magnesium stent degradation in porcine coronary arteries. Cardiovasc Revasc Med. 2008;9(4):248–54.PubMedCrossRef

79.

Serruys PW, Ormiston JA, Onuma Y, Regar E, Gonzalo N, Garcia-Garcia HM, et al. A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods. Lancet. 2009;373(9667):897–910.PubMedCrossRef

80.

Serruys PW, Onuma Y, Ormiston JA, de Bruyne B, Regar E, Dudek D, et al. Evaluation of the second generation of a bioresorbable everolimus drug-eluting vascular scaffold for treatment of de novo coronary artery stenosis: six-month clinical and imaging outcomes. Circulation. 2010;122(22):2301–12.PubMedCrossRef

81.

Onuma Y, Serruys PW, Perkins LE, Okamura T, Gonzalo N, Garcia-Garcia HM, et al. Intracoronary optical coherence tomography and histology at 1 month and 2, 3, and 4 years after implantation of everolimus-eluting bioresorbable vascular scaffolds in a porcine coronary artery model: an attempt to decipher the human optical coherence tomography images in the ABSORB trial. Circulation. 2010;122(22):2288–300.PubMedCrossRef

82.

Gomez-Lara J, Brugaletta S, Diletti R, Garg S, Onuma Y, Gogas BD, et al. A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds. Eur Heart J. 2011;32(3):294–304.PubMedCrossRef

83.

Gutierrez-Chico JL, Serruys PW, Girasis C, Garg S, Onuma Y, Brugaletta S, et al. Quantitative multi-modality imaging analysis of a fully bioresorbable stent: a head-to-head comparison between QCA, IVUS and OCT. Int J Cardiovasc Imaging. 2011.

84.

Okamura T, Serruys PW, Regar E. Cardiovascular flashlight. The fate of bioresorbable struts located at a side branch ostium: serial three-dimensional optical coherence tomography assessment. Eur Heart J. 2010;31(17):2179.PubMedCrossRef

85.

van Soest G, Goderie T, Regar E, Koljenovic S, van Leenders GL, Gonzalo N, et al. Atherosclerotic tissue characterization in vivo by optical coherence tomography attenuation imaging. J Biomed Opt. 2010;15(1):011105.PubMedCrossRef

86.

Giattina SD, Courtney BK, Herz PR, Harman M, Shortkroff S, Stamper DL, et al. Assessment of coronary plaque collagen with polarization sensitive optical coherence tomography (PS-OCT). Int J Cardiol. 2006;107(3):400–9.PubMedCrossRef

87.

Liu L, Gardecki JA, Nadkarni SK, Toussaint JD, Yagi Y, Bouma BE, et al. Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography. Nat Med. 2011;17(8):1010–4.PubMedCrossRef

Title: Optical Coherence Tomography: Potential Clinical Applications
Authors: Antonios Karanasos
Jurgen Ligthart
Karen Witberg
Gijs van Soest
Nico Bruining
Evelyn Regar
Publication date: 01-08-2012
Publisher: Current Science Inc.
Published in: Current Cardiovascular Imaging Reports / Issue 4/2012
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI: https://doi.org/10.1007/s12410-012-9140-x

ACC 2024 Congress Coverage

Heart Failure Video

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Optical Coherence Tomography: Potential Clinical Applications

Abstract

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2012

How Do OCT and IVUS Compare to Histology in Coronary Atherosclerosis and Stenting?

Three-Dimensional Fourier-Domain Optical Coherence Tomography Imaging: Advantages and Future Development

Molecular Imaging of Selectins in Endothelial Activation

Intracoronary IVUS for Evaluation of Atherosclerosis Progression

Optical Coherence Tomography Imaging: Novel Insights into the Vascular Response After Coronary Stent Implantation

Clinical Applications of Cardiac Magnetic Resonance Spectroscopy (CMRS)

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page