Published in:
01-08-2021 | Systemic Lupus Erythematosus | IMAGES THAT TEACH
A positive PYP scan: Thinking beyond amyloid
Authors:
Shaden Khalaf, MD, Najah Khan, MD, Mouaz Al-Mallah, MD, Mahwash Kassi, MD, Dipan Shah, MD
Published in:
Journal of Nuclear Cardiology
|
Issue 4/2021
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Excerpt
Hydroxychloroquine (HCQ), a medication prescribed for rheumatologic disorders, has life-threatening cardiac side effects, including QT prolongation, advanced AV block, and fatal cardiomyopathies, requiring discontinuation. HCQ cardiomyopathy can result in a false positive
99mTechnetium pyrophosphate (
99mTc-PYP)s scan,
1,
2 and is a diagnosis of exclusion. In non-ischemic cardiomyopathy (NICM) of unclear etiology, it is crucial to evaluate drug-induced cardiomyopathy. …