Published in:
01-08-2020 | Cardiomyopathy | Editorial
99mTc-aprotinin imaging in cardiac amyloidosis. Make an old tool new again?
Authors:
Riemer H. J. A. Slart, MD, PhD, Andor W. J. M. Glaudemans, MD, PhD, Walter Noordzij, MD, PhD, Hans L. A. Nienhuis, MD, PhD, Bouke P. C. Hazenberg, MD, PhD
Published in:
Journal of Nuclear Cardiology
|
Issue 4/2020
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Excerpt
Cardiac amyloidosis (CA) or amyloid cardiomyopathy (ACM), resulting from extracellular deposition of amyloid fibrils, is an underestimated cause of heart failure and cardiac arrhythmias.
1,
2 Amyloid cardiomyopathy is a restrictive form of cardiomyopathy (CM) characterized by diastolic dysfunction and should be suspected in any patient presented with heart failure with preserved ejection fraction (HFpEF). The two main types of cardiac amyloidosis are AL-type, derived from misfolded immunoglobulin light chains, and ATTR-type, derived from misfolded transthyretin (TTR) protein. …
